We conclude that the reasons of this difference are time of application, different laser parameters and type of
photosensitizing agent.
Caption: Figure 2: Advantages of using multicomponent
photosensitizing molecules and their different roles in TPDT: (1) Conjugating a PS to NPs and antibodies increases its stability in the circulation and tumour selectivity.
In this way, the aim of this study was to obtain a chromatographic method for AlPcCl determination in skin permeation studies, enabling the development of dermatological pharmaceutical systems containing this
photosensitizing agent.
In order to avoid photosensitive reactions, it is essential to know the
photosensitizing properties of such drugs and to advise the patients.
Therefore, the
photosensitizing AQ1 could be an alternative for the Candida infections treatment, which deserves further investigation.
* There was a low level of evidence supporting the non-PDT DL (809 to 980 nm) based on a small gain in clinical attachment loss (CAL) (0.21 mm) compared with SRP alone, although the ADA found a moderate level evidence supported the use of the PDT DL in conjunction with a
photosensitizing agent (0.53 mm gain in CAL).
(10) Other factors implicated in etiopathogensis are exposure to sunlight, (7,8)
photosensitizing medications, (6) mild ovarianor thyroid dysfuntion (10) and certain cosmetics.
The perfect
photosensitizing agent would be a single compound with high tumor selectivity and increased absorption of the red region of light in the treatment area for deeper tissue penetration.
The lack of photoprotection in insects confers a special advantage to the
photosensitizing compounds as substantially irresistible insecticides.
First, patients receive an intravenous injection of a
photosensitizing agent.
With this method, a
photosensitizing agent is activated by light at a specific wavelength that corresponds to maximum absorbance by the substance, resulting in the production of free radicals, singlet oxygen, and other reactive oxygen species, which have a toxic effect on bacterial cells, leading to cell death without causing harm to the host [6, 7, 11-13].
For photodynamic therapy, a
photosensitizing agent is applied to the cervix and accumulates in the premalignant cells, he explained.
