photosensitization

(redirected from photosensitisation)
Also found in: Dictionary, Thesaurus.

photosensitization

 [fo″to-sen″sĭ-tĭ-za´shun]
the development of abnormally heightened reactivity of the skin or eyes to sunlight; it can be caused by a wide variety of drugs and chemicals. phototoxic reactions occur when a given drug absorbs ultraviolet radiation from the sun and a sunburnlike response occurs in a short period of time. Within hours there is a burning sensation of the exposed skin, followed by redness and swelling. Within a day or two the skin becomes heavily pigmented and begins to peel; a severe reaction can cause scarring. Phototoxic reactions are more likely to occur in light-skinned persons than in those with darkly pigmented skin that can block harmful radiation.

Photoallergic reactions occur after an initial exposure to the drug or chemical which triggers the production of antibodies. On second exposure a skin eruption appears and there may be intense itching. It is possible for the eruption to appear on unexposed areas of skin as well as exposed areas. There is a long list of drugs that can cause this type of reaction; antineoplastics, antimicrobials, diuretics, hypoglycemic agents, and even antihistamines may trigger it in certain individuals.

pho·to·sen·si·ti·za·tion

(fō'tō-sen-si-ti-zā'shŭn),
1. Sensitization of the skin to light, usually due to the action of certain drugs, plants, or other substances; may occur shortly after administration of the drug (phototoxic sensitivity), or may occur only after a latent period of from days to months (photoallergic sensitivity, or photoallergy).

photosensitization

(fō′tō-sĕn′sĭ-tĭ-zā′shən)
n.
The act or process of inducing photosensitivity.

pho·to·sen·si·ti·za·tion

(fō'tō-sen'si-tī-zā'shŭn)
1. Sensitization of the skin to light, usually due to the action of some drugs, plants, or other substances; may occur shortly after administration of the drug (phototoxic sensitivity), or may occur only after a latent period of days to months (photoallergic sensitivity, or photoallergy).
References in periodicals archive ?
Based on history and specific dermatitis lesions, the cause for photosensitisation reaction was identified as lantana poisoning and managed successfully with parentral fluid therapy, hepatoprotective, anti inflammatory and topical peperations.
If the animal eats sufficient quantities of plant, photosensitisation sets in with liver damage and accumulation of phylloerythrin in blood, which sensitises animal's skin to ultra-violet light.
Mild photosensitisation to solar simulated radiation was detected with St.
The advantages conferred by the hypericum-cream tested here are the absence of any photosensitisation thanks to the use of a hypericin-free St.
The characteristics and performance criteria will be based on the solar photosensitisation processes and its effectiveness in reducing water borne infectious bacteria such as faecal coliforms.
The concept of photodynamic inactivation or photosensitisation of microorganisms evolved from experiments conducted in the early 19th century as sensitized photooxidation treatment used for the destruction of bacteria and viruses present in water [12, 14].