While photoreceptor layer
thickness abnormalities are present in the macular area, these abnormalities are not present in the peripapillary area.
The technology used for PRIMA is a sub-retinal stimulation, which targets the inner retina directly replacing the function of the photoreceptor layer
by a miniature wireless electrode holder, thus stimulating the inner retina.
A prospective observational study was carried out on 40 eyes of 40 patients (35 males and 5 females), age ranging from 26 to 51 years to evaluate the changes in macular photoreceptor layer using optical coherence tomography (OCT) in patients with central serous chorioretinopathy (CSC) and correlate the loss of visual acuity.
It was concluded that the preserved photoreceptor layer is associated with a higher and better corrected visual acuity compared with granulated photoreceptor layer.
By sectioning down through and microscopically examining each of the five layers of the retina, they knew when they had reached the photoreceptor layer
The RPE layer plays a central role in the health and function of the photoreceptor layer
The stress on the macula from the contracting vitreous causes stretching of the RPE layer, which subsequently will also push into the photoreceptor layer (Figure 6a).
It should be noted, however, that the level of VA in a lamellar hole will be much better than a full thickness macular hole, as the photoreceptor layer is left intact and does not detach.
Within 21 days, the new cells settled into the photoreceptor layer
and grew into rods and cones.
Although other parts of the eye still work, it might be possible to restore vision using an implant that mimics the photoreceptor layer
001 for the high dose group in each study), dose-dependent increase in retinal thickness involving photoreceptor layers
as measured by optical coherence tomography (OCT).