Retinitis pigmentosa-the most common cause of blindness in young people-occurs mostly due to loss of millions of light sensitive photoreceptor cells
that line the retina, Medical Xpress reported.
Scientists at the University of Queensland in Australia have discovered a new type of cell that displays properties of both rod and cone photoreceptor cells
The functional and structural abnormalities of photoreceptor cells
under high IOP are also noticed in glaucoma patients  and in primate glaucoma model.
In a study of transgenic mice carrying a copy of the mutated human gene (CEP290) targeted by our clinical candidate, EDIT-101, we demonstrated efficient transduction and gene editing in the retinal photoreceptor cells
, the relevant cell type affected in LCA10 patients.
Most cases of incurable blindness occur due to the loss of millions of light-sensitive photoreceptor cells
that function like camera sensors.
Lead researcher Dr Roly Megaw said that by furthering the understanding of the RPGR gene and its effects on photoreceptor cells
, they hope that these findings bring them closer to developing a possible treatment for this devastating disease.
Opsin expression, physiological characterization and identification of photoreceptor cells
in the dorsal rim area and main retina of the desert locust, Schistocerca gregaria.
In RP, which affects approximately 100,000 Americans and 1 in 4,000 persons worldwide, rod-specific genetic mutations cause rod photoreceptor cells
to dysfunction and degenerate over time.
Most people know at least a little about the retina, a thin tissue an inch in diameter that contains all the photoreceptor cells
responsible for beginning vision and their circuits that produce signals that become vision.
They enhance vision by absorbing scattered light and delivering nutrients to photoreceptor cells
The product will be delivered to patients upon diagnosis and is aimed at blocking photoreceptor cells
from dying until surgery can be completed.
In the retina, melatonin is released mainly by photoreceptor cells
but can be also produced by some other cells in pathological conditions .