The phototoxic and photoallergy
potential of clindamycin phosphate 1.2%/tretinoin 0.025% gel for facial acne: results of two single-center, evaluator-blinded, randomized, vehicle-controlled phase 1 studies in healthy volunteers.
Of particular interest is to know that MJ is well tolerated, and no meaningful local or systemic side effects have been detected in animal and humans trials after toxicology and dermatology studies for acute toxicity, skin irritation, mucous membrane (eye) irritation, skin sensitization, phototoxicity, and photoallergy
, not being toxic to healthy organisms of different species so far tested and emphasizing the safety of MJ use in humans [50-52].
Quinolonephotoconjugated major histocompatibility complex class II-binding peptides with lysine are antigenic for T cells mediating murine quinolone photoallergy
. J Invest Dermatol 2001; 117: 1206-1211.
Exogenously induced photosensitivity diseases include phototoxicity and photoallergy.
Phototoxicity can occur in anyone who has been exposed to photosensitizing drugs and light exposure, but photoallergy is limited to individuals who have been sensitized to a substance that is activated by light, Dr.
test checks for the possibility of induced allergic reaction of a product with sunscreen exposed to sunlight as it would be used by the consumer.
The following commonly used drugs have been implicated in causing phototoxicity and photoallergy
when used in conjunction with sunlight exposure:
It was hypothesized that chronic actinic dermatitis may be the final stage of a contact photoallergy
, contact ec-zema, drug photosensitivity, polymorphic light eruption, or en-dogenous eczema (8).
These light sources are used for clinical testing, SPF sunscreen testing, photobiology research, phototoxicity evaluations, photoallergy
studies, material testing and UV curing.
MAJOR SERVICES: Because of our 55 years of testing personal care products, Hill Top has unparalleled experience in cosmetic, antiperspirant, deodorant, sunscreen, aging skin, odor and malodor, periodontology, gingivitis & plaque, teeth whitening & stain, skin feel, skin irritation, skin sensitization, photoirritation, photoallergy
, exaggerated use, consumer use/preference and bioinstrumentation testing.