DABRA is a minimally invasive excimer laser photoablation
system that non-thermally, photochemically ablates channels in vascular blockages.
In contrast, UV lasers utilize a "cool" photochemical or photoablation
marking process that does not require high average power levels and allows damage-free marking on many materials in a hands-free, batch process.
Xanthelasma is considered as an ideal target for laser therapy because of its superficial location.5 Therefore, different ablative and non-ablative lasers have been tried in photoablation
of xanthelasmas includes; CO2 laser,1 erbium:yttrium-aluminum-garnet (Er:YAG) laser,6 Q-switched neodymium:yttrium-aluminum-garnet (Nd:YAG) laser,7 pulsed dye laser,8 and diode laser.
Cancer cells take up the photosensitizers, resulting in cell death because of photoablation
. To avoid nonspecific heating of healthy cells, photosensitizers must be selectively taken up by cancer cells.
Olmi et al., "Tumor-tropic endothelial colony forming cells (ECFCs) loaded with near-infrared sensitive Au nanoparticles: A "cellular stove" approach to the photoablation
of melanoma," Oncotarget, vol.
Srinivasan, "Corneal changes following collagen cross linking and simultaneous topography guided photoablation
with collagen cross linking for keratoconus," Indian Journal of Ophthalmology, vol.
The surgical resection as emergency approach is of limited value, due to multiple lesions (>100) and the diffuse bleeding pattern; photoablation
, endoscopic electrocautery and transcatheter embolization might prove useful in this context.
Then, with the help of spatula, the flap is lifted to allow the excimer laser to perform photoablation
However, a large amount of excimer laser photoablation
may result in the deterioration of superior intrinsic corneal optical characteristic .
Papucci et al., "Concomitant effect of topical ubiquinone Q10 and vitamin E to prevent keratocyte apoptosis after excimer laser photoablation
in rabbits," Journal of Refractive Surgery, vol.
(13) Peyman and Katoh in 1987 used an Erbium:YAG laser for inducing photoablation
on the lens nucleus.