phospholipase D


Also found in: Encyclopedia, Wikipedia.

phos·pho·lip·ase D

an enzyme that hydrolyzes phosphatidylcholine to produce choline and a phosphatidate; also acts on other phosphatidyl esters.
References in periodicals archive ?
The best results--70% of glyceryl ether phospholipid--were achieved utilizing 5% of phospholipase D and a limonene-acetate buffer at a ratio of 1-to-3 at an equimolar ratio of reactants.
Benson, "Transphosphatidylation by phospholipase D," Journal of Biological Chemistry, vol.
Zheng, "Cloning and expression of phosphatidylcholine-hydrolyzing phospholipase D from Ricinus communis L.," The Journal of Biological Chemistry, vol.
Wang, "Multiple forms of phospholipase D in plants: the gene family, catalytic and regulatory properties, and cellular functions," Progress in Lipid Research, vol.
PLD[alpha] is the conventional plant phospholipase D, the characteristic feature of which is the necessity of millimolar [Ca.sup.2+] for optimal activity in vitro.
Munnik, "The role of phospholipase D in plant stress responses," Current Opinion in Plant Biology, vol.
An, "Molecular cloning and partial characterization of a novel phospholipase D gene from Chorispora bungeana," Plant Cell, Tissue and Organ Culture, vol.
The genes studied were phospholipase D, phospholipase C, phospholipase [A.sub.2], GDSL-motif lipase/hydrolase, and a lysophospholipase.
Concomitant with the increase in total phospholipid content and the decrease in mismatched side chains, we observed an increase in activity (at the mRNA transcription level) of phospholipase D, phospholipase C, and phospholipase [A.sub.2].
Following the rapid augmentation, a structural re-engineering process occurs, resulting in a re-establishment of mismatched:matched acyl chain ratios and a decrease in transcriptional activity of phospholipase D and [A.sub.2].
The difference between WBCHO and PLCHO concentrations are explained by several mechanisms: intracellular generation of choline in blood cells by intracellularly located phospholipase D and cell activation pathways (3-7), existence of a choline transport system in blood cells (10), and the fact that choline is removed to a certain extent from plasma via cellular uptake by other tissues (11).
Activation of phospholipase D in human platelets by collagen and thrombin and its relationship to platelet aggregation.