Hydroxyl radicals are capable to damage the phosphoglyceride
membrane structures of cell membranes and its organelles.
The cell membrane consists of two identifiable layers, each of which is made up of an ordered row of phosphoglyceride
molecules such as phosphatidylcholine.
47 metabolites were found as potential biomarkers and indicated Ml would lead to disturbed metabolism due to inflammation, oxidative stress and structural damage; while GBE could effectively restore fatty acid, sphingolipid, phosphoglyceride
, glyceride, amino acid and energy metabolism, closely related to its antioxidant, PAF antagonist and hypolipidemic properties.
These parameters indicate notable interactions of phosphoglyceride
groups with lactophoricin-I squeezed into the subsurface region.
In our study, plasmalogens were not analyzed, but we identified 2 dimethylacetals, DMA 16 and DMA 18, that are indicative of the presence of this kind of phosphoglyceride
in the gonad.
The raft fractions were separated in OptiPrep centrifugal gradients and both the ergosterol concentrations and fatty acid profiles (as FAMEs) determined by GC following extraction and hydrolysis of phosphoglyceride
ester, sterol ester, and phytosphingosine amide linkages.
Platelet activating factor (PAF) is an alkyl phosphoglyceride
(1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) that is synthesized by numerous cells and tissues upon appropriate stimulation.
The neurotoxins have phospholipase A2 activity and hydrolyze phosphoglycerides
thereby producing neuromuscular blockade by inhibiting the release of acetylcholine from the presynaptic membrane.
Evidence that the basal turnover of phosphoglycerides
does not involve phospholipase D," Journal of Biological Chemistry, vol.
(1979) Metabolism of arachidonoyl phosphoglycerides
in mouse brain subcellular fractions.
n-3 and n-6 polyunsaturated fatty acids in the phosphoglycerides
of salt-secreting epithelia from two marine fish species.
Distribution and fatty acid composition of phosphoglycerides
in normal human brain.