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phosphoenol pyruvate

/phos·pho·enol ·py·ru·vate/ (-e″nol-pi´roo-vāt) a high energy derivative of pyruvate occurring as an intermediate in the Embden-Meyerhof pathway of glucose metabolism, in gluconeogenesis, and in the biosynthesis of some amino acids.

phosphoenolpyruvic acid or phosphoenolpyruvate (PEP)

a high-energy compound which when dephosphorylated to pyruvic acid, gives rise to the synthesis of ATP from ADP in GLYCOLYSIS.


an intermediary metabolite in the Embden-Myerhof glycolytic pathway; abbreviated PEP.
References in periodicals archive ?
In order to produce energy, the gluconeogenesis occurs in the phosphoenolpyruvate formation, with 1 GTP spent (step D3 in Figure 1), expressed in Equation (5).
A susceptibility locus for early-onset non-insulin dependent (type 2) diabetes mellitus maps to chromosome 20q, proximal to the phosphoenolpyruvate carboxykinase gene.
Developmental profiles for the activity, concentration, and molecular structure of the pyrophosphate and ATP-dependent phosphofructokinases, phosphoenolpyruvate carboxylase and pyruvate kinase.
The upregulated glycolysis consequent to the Warburg phenotype produces phosphoenolpyruvate, a basic substrate for the bacterial shikimic acid pathway which can synthesise monoamines and neuroactive alkaloids.
0]' of hydrolysis of ATP is smaller than that of other phosphates such as phosphoenolpyruvate [14, 15].
Previously, it was believed that only phosphoenolpyruvate (PEP) carboxylase is activated for maintaining the oxaloacetate pool during growth on glucose alone (Mori and Shiio, 1985).
Wild and Maddison (2008) evaluated the phylogenetic performance of 9 nuclear genes (alpha-spectrin (AS), RNA polymerase H (RNA Pol II), topoisomerase I (TOP1), arginine kinase (AK), carbamoylphosphate synthase domain (CAD), enolase, phosphoenolpyruvate carboxykinase (PEPCK), wingless (WG), and 28S) sequenced from 31 beetles in 18 genera representing all suborders except Myxophaga (but focused on Adephaga), and 2 outgroups.
Suppression of phosphoenolpyruvate carboxykinase gene expression by secoisolariciresinol diglucoside (SDG), a new antidiabetic agent.
47) A new variety of corn was developed by overexpression of phosphoenolpyruvate carboxylase (PEPC), yielding broader leaves and high biomass density because of greater CO 2 fixation.
In addition, they said that phosphoenolpyruvate carboxykinase (PEPCK) plays a pivotal role in the growth and survival of Mtb during infections in mice, making PEPCK a potential target for drugs that fight tuberculosis.
9,10,12,31,32) Glyceroneogenesis, controlled by phosphoenolpyruvate carboxykinase, or PEPCK, produces glycerol to complete this cycle, because the glycerol released by lipolysis is exported, rather than recycled.

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