Also found in: Acronyms, Encyclopedia, Wikipedia.

phosphoenolpyruvic acid or phosphoenolpyruvate (PEP)

a high-energy compound which when dephosphorylated to pyruvic acid, gives rise to the synthesis of ATP from ADP in GLYCOLYSIS.
References in periodicals archive ?
The PC catalyzes the conversion of pyruvate to oxaloacetate, and cytosolic PEPCK catalyzes the conversion of oxaloacetate to phosphoenolpyruvate. Both enzymes have been shown to respond to the onset of lactation.
Pyruvate then proceeds to phosphoenolpyruvate by the enzymes pyruvate carboxylase and PEPCK (10,35).
Markers Group p values (a) Primary Metastatic group group Syn 0.557 Positive 12 31 Negative 0 3 CgA 1.000 Positive 9 23 Negative 3 10 CD56 0.659 Positive 9 26 Negative 1 8 Glypican-3 0.175 Positive 4 3 Negative 5 15 PCK 0.286 Positive 7 20 Negative 1 0 CK7 0.438 Positive 5 15 Negative 5 7 CK19 Positive 6 18 Negative 3 5 0.654 EMA 1.000 Positive 4 11 Negative 1 3 Syn = synaptophysin, CgA = chromogranin A, PCK = phosphoenolpyruvate carboxykinase, CK7 = cytokeratin 7, TTF-1 = thyroid transcription factor, CK19 = cytokeratin 19, EMA = epithelial membrane antigen.
ENO1, also called alpha-enolase, is a key glycolytic enzyme catalyzing the conversion of 2-phospho-D-glycerate to phosphoenolpyruvate [9, 16].
Granner, "The synergistic effect of dexamethasone and all-trans-retinoic acid on hepatic phosphoenolpyruvate carboxykinase gene expression involves the coactivator p300," Journal of Biological Chemistry, vol.
Macintyre et al., "Phosphoenolpyruvate is a metabolic checkpoint of anti-tumor T cell responses," Cell, vol.
Gene symbol Gene name GO biological process TPP ITIH1 Inter-alpha-trypsin Hyaluronan metabolic inhibitor heavy chain 1 process PCK1 Phosphoenolpyruvate Glucose metabolic process carboxykinase 1 FABP4 Fatty acid binding Cholesterol homeostasis 4 protein GPBAR1 G-protein-coupled bile Cell surface bile acid acid receptor 1 receptor signaling pathway PPP1R1A Protein phosphatase 1 Glycogen metabolic regulatory inhibitor process subunit 1A SLC04C1 Solute carrier organic Cell differentiation anion transporter family, member 4C1 FNDC5 Fibronectin type III Response to muscle domain-containing protein activity 5 ADIPOQ Adiponectin.
Phosphoenolpyruvate + [HC03.sup.-] [right arrow] oxaloacetate + [H2P04.sup.-]
Insulinotropic effect of cinnamaldehyde on transcriptional regulation of pyruvate kinase, phosphoenolpyruvate carboxykinase, and GLUT4 translocation in experimental diabetic rats.
The substrates for ComA are phosphoenolpyruvate and sulfite, and the enzyme produces (R)-phosphosulfolactate, which is then dephosphorylated by ComB to produce (R)-sulfolactate.

Full browser ?