phosphodiesterase type 5 inhibitors

phosphodiesterase type 5 inhibitors

Drugs used to treat impotence. Examples are SILDENAFIL (Viagra), tadalafil (Cialis) and VARDENAFIL (Levitra).
References in periodicals archive ?
The effects of phosphodiesterase type 5 inhibitors on penile rigidity variables during a period with no sexual stimulation: A laboratory setting double-blind study.
Patients with symptomatic PH in WHO FC III or IV at baseline were allowed to receive PAH background therapy throughout the study, including phosphodiesterase type 5 inhibitors and/or oral/inhaled prostanoids.
Mostafa, "Oral phosphodiesterase type 5 inhibitors: nonerectogenic beneficial uses, " Journal of Sexual Medicine, vol.
Phosphodiesterase type 5 inhibitors (PDE5) are a group of drugs (sildenafil, tadalafil, vardanafil) that are widely used as a standard treatment for erectile dysfunction (ED) and some of them for pulmonary hypertension as well (sildenafil and tadalafil).
Data from these three trials show that testosterone supplementation yields some benefits, but they were modest, tended to wane toward the end of the year of treatment, and were not as robust as those reported with use of phosphodiesterase type 5 inhibitors. These results might be insufficient to support a decision to initiate testosterone therapy in symptomatic older men.
Pharmacokinetics, pharmacodynamics and efficacy of phosphodiesterase type 5 inhibitors. J Am Osteopath Assoc 2004; 104(3 suppl.
Effects of two selective phosphodiesterase type 5 inhibitors, sildenafil and vardenafil, on object recognition memory and hippocampal cyclic GMP levels in the rat.
* Phosphodiesterase type 5 inhibitors are not FDA-approved for sexual dysfunction in women.
Tests conducted by the agency "have revealed an alarming variety of undeclared active ingredients in products marketed as dietary supplements," including phosphodiesterase type 5 inhibitors, such as sildenafil; anticoagulants, such as warfarin; beta-blockers, such as propranolol; and anticonvulsants, such as phenytoin, the letter said.
Also, use of other phosphodiesterase type 5 inhibitors (PDE-5i) drugs such as Cialis and Levitra can be harmful for the ear, but results on those drugs are inconclusive.

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