In addition reduced surfactant phospholipid, phosphatidylglycerol
and phosphatidic acid along with increase in surface active lipids phosphatidylserine and phosphatidylinositol in alveolar epithelium may decrease alveolar septation and reduce lung compliance and surfactant adsorption.
The lipid is mainly dipalmitoylphosphatidylcholine (lecithin- 65%), phosphatidylglycerol
, apoproteins (5%) and cholesterol.
2]-IIA preferentially hydrolyzes PE and phosphatidylglycerol
, which are enriched in bacterial membranes.
Balazova, "Specific degradation of phosphatidylglycerol
is necessary for proper mitochondrial morphology and function," Biochimica et Biophysica Acta (BBA)--Bioenergetics, vol.
mostly phosphatidylethanolamine and phosphatidylglycerol
, which are
phosphatidylcholine, PC; phosphatidylglycerol
, PG), whereas others are inverted hexagonal phase or nonbilayer forming lipids (e.
Measurement of the lecithin/sphingomyelin ratio and phosphatidylglycerol
in aminotic fluid: an accurate method for the assessment of fetal lung maturity.
Major polar lipids are phosphatidylglycerol
diphosphatidylglycerol and phosphatidylethanolamine.
7% of these phospholipids is composed of phosphatidylcholine (PTC) and 8-12% is composed of phosphatidylglycerol
(PTG), phosphatidylinositol (PTI) and phosphatidylethanolamine (PTE).
Other FLM tests still in use today include the lecithin-to-sphingomyelin (L/S) ratio, the qualitative detection of phosphatidylglycerol
(PG), and the lamellar body count (LBC).
In previous work, we have detected phospholipid species, such as phosphatidylcholine and phosphatidylglycerol
, that were consistent with an RTLF composition (10).
Tap test, shake test and phosphatidylglycerol
in the assessment of fetal pulmonary maturity.