phosphatidate phosphatase

phos·pha·ti·date phos·pha·tase

an enzyme that catalyzes the hydrolysis of phosphatidate producing orthophosphate and 1,2-diacylglycerol; this enzyme participates in phospholipid and triacylglycerol metabolism.
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2+]-dependent phosphatidate phosphatase (PAP) and catalyze the penultimate step of converting phosphatidic acid (PA) to diacylglycerol (DAG) in the glycerol phosphate pathway (Han et al.
A conserved serine residue is required for the phosphatidate phosphatase activity but not the transcriptional coactivator functions of lipin-1 and lipin-2.
Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns.