phosphatidate phosphatase

phos·pha·ti·date phos·pha·tase

an enzyme that catalyzes the hydrolysis of phosphatidate producing orthophosphate and 1,2-diacylglycerol; this enzyme participates in phospholipid and triacylglycerol metabolism.
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A conserved serine residue is required for the phosphatidate phosphatase activity but not the transcriptional coactivator functions of lipin-1 and lipin-2.
Three mammalian lipins act as phosphatidate phosphatases with distinct tissue expression patterns.
Temporal and spatial regulation of the phosphatidate phosphatases lipin 1 and 2.