phosphate binder


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binder

 [bīnd´er]
1. a support bandage that wraps around the chest or abdomen and is secured with ties or Velcro.
Abdominal binders. A, Scultetus. B, Straight. From Elkin et al., 2000.
2. a substance that attaches to another, such as to facilitate its removal from the body; see bind (def. 2).
phosphate binder a substance such as aluminum hydroxide, calcium acetate, or calcium carbonate that binds phosphate in the blood, removing it from circulation; used in treatment of hyperphosphatemia, such as in patients with end-stage renal disease or hypoparathyroidism.

phosphate binder

Any of various medications used to prevent hyperphosphatemia in patients with end-stage renal disease. Calcium carbonate taken with meals is the most commonly employed agent. In the past aluminum-containing antacids were used for this purpose, but this practice is now avoided because of the toxic accumulation of aluminum in patients with renal failure.
See also: binder
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References in periodicals archive ?
At the OTU level, 58 OTUs were different before and after the use of phosphate binder. More decreased OTUs were identified after using the phosphate binder [Figure 2].{Figure 2}
Relationship between Gut Microbiota and Phosphorus Metabolism in Hemodialysis Patients: A Preliminary Exploration
Phosphate binders, widely used to decrease oral phosphate absorption, are the mainstay of treatment.
Colonic Mucosal Ulceration and Gastrointestinal Bleeding Associated with Sevelamer Crystal Deposition in a Patient with End Stage Renal Disease
* Phosphate binders are recommended by the KDIGO guidelines for use in patients with kidney disease and hyperphosphatemia.
Bone disease in patients with kidney disease: a tricky interplay
Effects of sevelamer and calcium-based phosphate binders on mortality in hemodialysis patients.
Alteraciones del metabolismo mineral y oseo asociadas a la enfermedad renal cronica
study; intake of vitamin D metabolites and phosphate binders, cumulative
Parameters of hemodialysis adequacy and patients' survival depending on treatment modalities/Parametri adekvatnosti hemodijalize i prezivljavanje bolesnika u zavisnosti od modaliteta lecenja
Long-term comparison of a calcium-free phosphate binder and calcium carbonate-phosphorus metabolism and cardiovascular calcifications.
Longitudinal observations on the mineral metabolism of dialysis patients at the University Hospital
Phosphate Binders. To improve clinical outcomes in CKD patients, one of the key therapeutic goals is to lower the phosphate load and maintain serum phosphorus levels within the normal range [183].
Vascular calcification and renal bone disorders
Because FGF23 is a phosphaturic hormone, its level might be modifiable by dietary phosphate restriction or using phosphate binders. In non-CKD patients (healthy adults), reducing dietary phosphate intake lowers FGF23 levels [80, 81].
Cardiovascular risk factors and chronic kidney disease--FGF23: a key molecule in the cardiovascular disease
In our study, we did not assess inadequate phosphate binder dosage as a reason for elevated phosphate levels; however, inadequate phosphate binder dosing may be a potential reason for inability to achieve lower phosphate control in our cohort.
A novel, 12-week, nurse-led motivation and education programme has no effect on serum phosphate levels in haemodialysis patients
Thus, patients are required to take phosphate binders in an attempt to achieve adequate serum phosphorus levels.
A randomized, controlled, three-arm, open-label, cross-over bioequivalence study comparing calcium acetate oral solution and calcium acetate gelcaps in healthy volunteers
Oral phosphate binders play the central role in the control of hyperphosphatemia.
The effect of coadminstration of nicotinamide and calcium-based phosphate binder on hyperphophatemia in patients undergoing hemodialysis

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