phosphate binder


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binder

 [bīnd´er]
1. a support bandage that wraps around the chest or abdomen and is secured with ties or Velcro.
Abdominal binders. A, Scultetus. B, Straight. From Elkin et al., 2000.
2. a substance that attaches to another, such as to facilitate its removal from the body; see bind (def. 2).
phosphate binder a substance such as aluminum hydroxide, calcium acetate, or calcium carbonate that binds phosphate in the blood, removing it from circulation; used in treatment of hyperphosphatemia, such as in patients with end-stage renal disease or hypoparathyroidism.

phosphate binder

a substance, such as aluminum hydroxide, calcium acetate, or calcium carbonate, that binds phosphate in the blood, removing it from circulation. It is used in treatment of hyperphosphatemia in patients with end-stage renal disease or hypoparathyroidism.

phosphate binder

Any of various medications used to prevent hyperphosphatemia in patients with end-stage renal disease. Calcium carbonate taken with meals is the most commonly employed agent. In the past aluminum-containing antacids were used for this purpose, but this practice is now avoided because of the toxic accumulation of aluminum in patients with renal failure.
See also: binder
References in periodicals archive ?
Invented in the UK and exclusively licensed from the Medical Research Council, PT20 is a novel iron-based phosphate binder being developed for the eventual treatment of hyperphosphataemia related to dialysis-dependent and dialysis-independent chronic kidney disease.
Inclusion criteria included: age greater than 18 years, on chronic hemodialysis for at least three months, use of a phosphate binder before entry into the study with an average serum calcium between 2.
ESRD patients with hyperphosphataemia are prescribed phosphate binders to reduce the amount of phosphorus absorbed by the body.
note in Guideline 5, Use of Phosphate Binders in Chronic Kidney Disease (CKD), that
Ester-cured phenolics, urea-free furans, silicates and inorganic phosphate binders contain little or no nitrogen.
As diet and dialysis are rarely effective alone in meeting the target phosphate levels over ninety per cent of patients on dialysis support will use a phosphate binder.
Another approach is to try lanthanum or another phosphate binder.
Ironically, some currently available phosphate binders - although they help
and EU5 nephrologists from approximately 1,870 dialysis patient charts combined, ESAs and phosphate binders are the most commonly used renal medications in dialysis patients; however, the use of IV iron differs considerably between the two regions.
Several studies have shown that higher serum phosphorus concentrations may be associated with increased mortality and morbidity in CKD, however, no phosphate binders are currently FDA approved for NDD-CKD.
Mortality effect of coronary calcification and phosphate binder choice in incident hemodialysis patients.
Renvela is a next generation version of Renagel, a calcium-free metal free, non-absorbed phosphate binder, and has the added benefit of a carbonate filter.