phosphate binder


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binder

 [bīnd´er]
1. a support bandage that wraps around the chest or abdomen and is secured with ties or Velcro.
Abdominal binders. A, Scultetus. B, Straight. From Elkin et al., 2000.
2. a substance that attaches to another, such as to facilitate its removal from the body; see bind (def. 2).
phosphate binder a substance such as aluminum hydroxide, calcium acetate, or calcium carbonate that binds phosphate in the blood, removing it from circulation; used in treatment of hyperphosphatemia, such as in patients with end-stage renal disease or hypoparathyroidism.

phosphate binder

Any of various medications used to prevent hyperphosphatemia in patients with end-stage renal disease. Calcium carbonate taken with meals is the most commonly employed agent. In the past aluminum-containing antacids were used for this purpose, but this practice is now avoided because of the toxic accumulation of aluminum in patients with renal failure.
See also: binder
References in periodicals archive ?
At the OTU level, 58 OTUs were different before and after the use of phosphate binder. More decreased OTUs were identified after using the phosphate binder [Figure 2].{Figure 2}
Phosphate binders, widely used to decrease oral phosphate absorption, are the mainstay of treatment.
* Phosphate binders are recommended by the KDIGO guidelines for use in patients with kidney disease and hyperphosphatemia.
Effects of sevelamer and calcium-based phosphate binders on mortality in hemodialysis patients.
Long-term comparison of a calcium-free phosphate binder and calcium carbonate-phosphorus metabolism and cardiovascular calcifications.
Phosphate Binders. To improve clinical outcomes in CKD patients, one of the key therapeutic goals is to lower the phosphate load and maintain serum phosphorus levels within the normal range [183].
Because FGF23 is a phosphaturic hormone, its level might be modifiable by dietary phosphate restriction or using phosphate binders. In non-CKD patients (healthy adults), reducing dietary phosphate intake lowers FGF23 levels [80, 81].
In our study, we did not assess inadequate phosphate binder dosage as a reason for elevated phosphate levels; however, inadequate phosphate binder dosing may be a potential reason for inability to achieve lower phosphate control in our cohort.