phosphate binder


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binder

 [bīnd´er]
1. a support bandage that wraps around the chest or abdomen and is secured with ties or Velcro.
Abdominal binders. A, Scultetus. B, Straight. From Elkin et al., 2000.
2. a substance that attaches to another, such as to facilitate its removal from the body; see bind (def. 2).
phosphate binder a substance such as aluminum hydroxide, calcium acetate, or calcium carbonate that binds phosphate in the blood, removing it from circulation; used in treatment of hyperphosphatemia, such as in patients with end-stage renal disease or hypoparathyroidism.

phosphate binder

a substance, such as aluminum hydroxide, calcium acetate, or calcium carbonate, that binds phosphate in the blood, removing it from circulation. It is used in treatment of hyperphosphatemia in patients with end-stage renal disease or hypoparathyroidism.

phosphate binder

Any of various medications used to prevent hyperphosphatemia in patients with end-stage renal disease. Calcium carbonate taken with meals is the most commonly employed agent. In the past aluminum-containing antacids were used for this purpose, but this practice is now avoided because of the toxic accumulation of aluminum in patients with renal failure.
See also: binder
References in periodicals archive ?
6) Maintaining an appropriate phosphorus level is accomplished through dietary phosphate restriction, the use of phosphate binders, and, in dialyzed patients, dialytic removal of phosphate.
The medications evaluated were vitamin D analogs (paricalcitol and calcitriol), phosphate binders (calcium acetate and sevelamer), and a calcium-sensing receptor sensitizer (cinacalcet).
Education regarding the importance of phosphate binders and compliance with medication was provided by dialysis nurses and patient participation was tracked on a "Tally board" within each unit.
The phenolic urethane, new urethane, furan, phenolic, alkyd oil and inorganic phosphate binders at one pass have been successfully reclaimed at high levels (90%).
Lanthanum carbonate (Fosrenol[R]) is a non-aluminum, non-calcium phosphate binder that first gained approval from Health Canada in 2006 for the treatment of hyperphosphatemia in dialysis patients (Health Canada, 2007).
Dietary restriction is absolutely necessary because of the limited binding capacity of the phosphate binders.
At the same time, the increased dialysis length was associated with better control of hyperphosphatemia and prevention of secondary hyperparathyreoidism, along with reduced frequency of administration of phosphate binders and metabolite of vitamin D [10-13].
Her elevated calcium x phosphorus product with very high serum parathyroid hormone levels further confirmed non-compliance with treatment, phosphate binders, and diet (see Table 1).
Fermagate Tablets, which is a new phosphate binder, has been shown to be safe and effective in treating hyperphosphatemia in phase 2 and 3 trials in CKD patients undergoing chronic haemodialysis.
Two studies (n=29) compared calcium carbonate with aluminium hydroxide as phosphate binder.
New York, NY announced it has reached agreement with the FDA regarding a Special Protocol Assessment (SPA) on the design of a Phase 3 clinical program for Zerenex (ferric citrate), its iron-based phosphate binder for the treatment of elevated serum phosphorous levels (hyperphosphatemia), in patients with end stage renal disease (ESRD).
University, examined the interaction of levothyroxine with two relatively new drugs--colesevelam (Welchol), the newest bile acid sequestrant approved for hyperlipidemia and diabetes; and lanthanum carbonate (Fosrenol), a new phosphate binder used in end-stage renal disease.