phosphatase


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Related to phosphatase: alkaline phosphatase, acid phosphatase

phosphatase

 [fos´fah-tās]
any of a group of enzymes capable of catalyzing the hydrolysis of esterified phosphoric acid, with liberation of inorganic phosphate, found in practically all tissues, body fluids, and cells, including erythrocytes and leukocytes.
acid phosphatase see acid phosphatase.
alkaline phosphatase see alkaline phosphatase.

phos·pha·tase

(fos'fă-tās),
Any of a group of enzymes (EC 3.1.3.x) that liberate orthophosphate from phosphoric esters.
See also: phosphohydrolases.

phosphatase

/phos·pha·tase/ (-tās) any of a group of enzymes that catalyze the hydrolytic cleavage of inorganic phosphate from esters.

phosphatase

(fŏs′fə-tās′, -tāz′)
n.
Any of numerous enzymes that catalyze the removal of phosphate groups by hydrolysis of phosphate ester bonds. They act in the opposite manner to kinases and are important in metabolism and cell signaling.

phosphatase

[fos′fətāz]
an enzyme that acts as a catalyst in chemical reactions involving phosphorus. It is present in serum, semen, the kidney, and the prostate. It is essential in the calcification of bone. See also catalyst, enzyme.

phos·pha·tase

(fos'fă-tās)
Any of a group of enzymes (EC sub-subclass 3.1.3) that liberate inorganic phosphate from phosphoric esters.

phosphatase

An enzyme that removes phosphate groups from a molecule.

phosphatase

an enzyme that catalyses the release of phosphate from a molecule. For example, in the mammalian liver phosphorylated glucose can be broken down to glucose with a phosphatase enzyme. see GLYCOGEN.

phos·pha·tase

(fos'fă-tās)
Any of a group of enzymes (EC sub-subclass 3.1.3) that liberate inorganic phosphate from phosphoric esters.

phosphatase(s) (fos´fətās),

n a group of enzymes that are distributed throughout most cells and body fluids and are characterized by their ability to hydrolyze a wide variety of monophosphate esters to alcohols and inorganic phosphate.
phosphatase, acid,
n a group of phosphatases (e.g., serum, liver, prostate) with optimal activity below a pH level of 7. Elevated serum levels have been observed in metastatic breast and prostatic cancer; Paget's, Gaucher's, and Niemann-Pick diseases and in myelocytic leukemia.
phosphatase, alkaline,
n a group of phosphatases (e.g., serum, liver, bone) whose optimal activity ranges near a pH level of 9.8. Elevated blood levels occur in Paget's disease and pregnancy, whereas low levels are characteristic of dwarfism and a generalized nutritional protein deficiency.

phosphatase

any of a group of enzymes capable of catalyzing the hydrolysis of esterified phosphoric acid, with liberation of inorganic phosphate, found in practically all tissues, body fluids and cells, including erythrocytes and leukocytes.

acid phosphatase
a lysosomal enzyme that hydrolyzes phosphate esters liberating phosphate, showing optimal activity at a pH between 3 and 6; found in erythrocytes, prostatic tissue, spleen, kidney and other tissues.
alkaline phosphatase
an isoenzyme showing optimal activity at a pH of about 10; found in bone, liver, kidney, leukocytes, adrenal cortex and other tissues, often used in clinical diagnosis of liver and/or bone damage. Called also AP; see also alkaline phosphatase.
phosphatase inhibitor-1
inhibitor of phosphatase enzymes known to activate glycogen synthesis or inactivate glycogen breakdown. Need to themselves be phosphorylated by cAMP-dependent kinases before they are effective in their inhibitory activity.
References in periodicals archive ?
NCTD is potent serine/threonine protein phosphatase 1 and protein phosphatase 2A (PP1 and PP2A) inhibitors.
It was divided into two portionsone portion was used for the determination of thyroid profile markers by Elisa methods and the other portion was used for the determination of serum alkaline phosphatase, serum calcium and serum Zn level using standard protocols.
Assessment of the serum levels of bone alkaline phosphatase with a new immunoradiometric assay in patients with metabolic bone disease.
The aim of this work was to study the effect of salinity on germination, seedling growth and acid phosphatase of Linum usitatissimum seeds.
The report reviews Alkaline Phosphatase (ALKP or Phosphomonoesterase or Glycerophosphatase or Alkaline Phosphohydrolase or EC 3.
The phosphatidylinositol-glycolipid anchoron alkaline phosphatase facilitates mineralization initiation in vitro.
Alkaline phosphatase activity was assayed using p- nitrophenyl phosphate as a substrate and incubation of sample was done for 1h at 37C.
Dr Rita Tewari of the University of Nottingham has completed what she describes as a 'Herculean study', has said that the latest study identifies how protein phosphatases regulate parasite development and differentiation and the research provides a systematic functional analysis for all the 30 phosphatases in Plasmodium berghei, which is the parasite responsible for causing malaria in rodents.
Rhizosphere soil has been shown to have up to eight times more phosphatase activity than bulk soil (Tarafdar and Jungk 1987; Fox and Comerford 1992), illustrating the role of enzyme-mediated organic-P cycling.