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A dihydrochalcone occurring in many parts of the apple tree; used experimentally to produce glycosuria in animals.
Synonym(s): phlorizin


, phlorizin, phloridzin (flōr′ĭ-zĭn, flŏ-rīz′ĭn) (flōr′ĭd-zĭn, flŏ-rid′zĭn) [Gr. phloios, phloos, bark + rhizo- + -in]
A glycoside present in the bark of some fruit trees. It is a powerful inhibitor of sugar transport in some animals.

phloridzin, phlorizin

a dihydrochalcone extracted from the root bark of the apple tree. Thought at one time to be present in cherry, plum and pear. Blocks the renal tubular reabsorption of glucose hence promoting the development of glycosuria.
References in periodicals archive ?
At present most of the phlorizin applied to business is isolated from the root of apple trees, but its application has been largely restricted because of high production cost.
Keywords: Glucose-6-phosphatase, nuclear envelope, microsomes, phlorizin.
extracts: chlorogenic acid, syrigin, procyanidin B2, caffeic acid, (-)-epicatechin, cinnamic acid, coumaric acid, phlorizin and quercetin, as described by others.
Effect of phlorizin on SGLT2 expression in the kidney of diabetic rats," Journal of Nephrology, vol.
Effects of hyperglycemia on glucose transporters of the muscle: use of the renal glucose reabsorption inhibitor phlorizin to control glycemia.
French researchers found they contain a flavonoid called phlorizin, which can increase the density of your bones and may help to protect post-menopausal women from the brittle bone disease osteoporosis.
isolated phlorizin from Eleutherococcus senticosus and studied its potential on human keratinocytes and skin equivalents.
Concentration Food item Edible part (mg/100g) * Major polyphenol (classes) Apples Peel Flesh 50-120$ ($) Phlorizin, phenolic acids: Total 0.
French scientists have discovered that apples contain flavonoids called phlorizin that protect bones from the brittle bone disease osteoporosis.
Hydrolysis by lactase phlorizin hydrolase is the first step in the uptake of daidzein glucosides by rat small intestine in vitro.