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A dihydrochalcone occurring in many parts of the apple tree; used experimentally to produce glycosuria in animals.
Synonym(s): phlorizin
Farlex Partner Medical Dictionary © Farlex 2012


, phlorizin, phloridzin (flōr′ĭ-zĭn, flŏ-rīz′ĭn) (flōr′ĭd-zĭn, flŏ-rid′zĭn) [Gr. phloios, phloos, bark + rhizo- + -in]
A glycoside present in the bark of some fruit trees. It is a powerful inhibitor of sugar transport in some animals.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Phloridzin widely exists in the fruit, leaf, stem and root of the apple tree.
In 2016, scientists gave phloridzin to mice that had been fed a high-fat diet that induced obesity.
Hyperoside, rutin, quercitrin, phloridzin, phloretin, caffeic acid, and chlorogenic acid standards were purchased from Extrasynthese (Genay, France), (+)-catechin and (-)-epicatechin from Fluka (Buchs, Switzerland) and avicularin and isoquercitrin from Chromadex (Santa Ana, USA).
Phenolic compounds: Considering the phenolic compound contents of the cherry cultivars grown in Mardin region, it was identified that gallic acid content ranged between 42.33-95.51 mg/100 g, catechin content between 1.76-5.02 mg/kg, chlorogenic acid content between 1.59-0.98 mg/100 g, caffeic acid content between 9.73-29.02 mg/100 g, cyringic acid content between 4.54-11.72 mg/100 g, p-coumaric acid content between 2.37-11.77 mg/100 g, ferulic acid content between 13.42-20.96 mg/100 g, o-coumaric acid content between 10.42-21.69 mg/100 g, phloridzin content between 4.55-10.45 mg/100 g, protocatechuic acid content between 1.26-5.32 mg/100 g, vanillic acid content between 17.06-32.49 mg/100 g, rutin content between 5.45-26.76 mg/100 g and quercetin content between 8.46-14.32 mg/100 g.
The main component was phloridzin [18], and there has been a patent to disclose a preparation method and application as antidiabetic, hypolipidemic, antioxidant, and antitumor medicine of M.
[49] also reported that apple polyphenol-phloretin traps more than 80% MGO within 10 min, and phloridzin traps more than 70% MGO within 24 h under physiological conditions.
Experimental study on the treatment of diabetes by phloridzin in rats.
The possible reason for this is a compound called Phloridzin which is present in apples and has similar characteristics of female sex hormone Estradiol.
Hyperoside, rutin, quercitrin, phloridzin, procyanidinB1 and procyanidin B2, and chlorogenic acid standards were purchased from Extrasynthese (Genay, France), (+)-catechin and (-)-epicatechin from Fluka (Buchs, Switzerland), and avicularin and isoquercitrin from Chromadex (Santa Ana, USA).
Ito, "Pathogenicity to apple branch and phloridzin degrading activity of Valsa caratosperma isolated from some broad leaf trees including apple tree," Annual Report of the Society of Plant Protection of North Japan, vol.
The first action works to smooth dimpled skin using slimming actives xanthoxyline, caffeine and phloridzin; the second "resculpts," using a complex formulated with ivy to boost elastin and strengthen collagen; and for the final action, xanthoxyline works to limit the development of new fat cells thereby helping to prevent recurrence, according to the company.