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A dihydrochalcone occurring in many parts of the apple tree; used experimentally to produce glycosuria in animals.
Synonym(s): phlorizin


, phlorizin, phloridzin (flōr′ĭ-zĭn, flŏ-rīz′ĭn) (flōr′ĭd-zĭn, flŏ-rid′zĭn) [Gr. phloios, phloos, bark + rhizo- + -in]
A glycoside present in the bark of some fruit trees. It is a powerful inhibitor of sugar transport in some animals.

phloridzin, phlorizin

a dihydrochalcone extracted from the root bark of the apple tree. Thought at one time to be present in cherry, plum and pear. Blocks the renal tubular reabsorption of glucose hence promoting the development of glycosuria.
References in periodicals archive ?
Phloridzin, has been used in diabetes research and has a low incidence of side effects.
One of the ways in which phloridzin reduces sugar in your blood is to inhibit the "carrier proteins" that absorb glucose from your intestine and kidney.
Howard, The apparent involvement of polyphenol oxidase and phloridzin in the production of apple rooting co-factors.
Effect of phloridzin and phloroglucinol on apple shoots.
2) When scientists added the unique apple polyphenol phloridzin to yeast cells in culture, they found that treated cultures lived an average of 2.
12-14) Phloridzin is especially active against glycation, one of the most common, preventable, and reversible causes of aging.
Anti-aging effects of phloridzin, an apple polyphenol, on yeast via the SOD and Sir2 genes.
Due to the flavonoid called phloridzin, which is found only in apples, French researchers have discovered that eating apples may help to prevent osteoporosis and may increase bone density, especially in post-menopausal women.
To further differentiate this product line, Diana has added the following trademarks to ingredients in the line: HealSea fucus extract for cardiovascular health; ChondrActiv joint health product; Brassicare broccoli extract standardized to glucoraphane; Appl'ln apple extract with 80% polyphenols and 5% phloridzin for weight management applications; and CranPure cranberry extract with 30% PACs.
The dihydrochalcone-O-glucoside, phloridzin, contributes to lower blood glucose by inhibiting glucose reabsorption from the urinary filtrate by sodium glucose co-transporters (White 2010).
Phytonutriance[R] Appl'In[TM] apple extract with 80% polyphenols, 5% phloridzin for weight management
Based on the high procyanidin content of apples, which also contain a unique polyphenol known as phloridzin, modern science is now confirming the truth of this old adage.