phenytoin-induced gingival overgrowth


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phenytoin-induced gingival overgrowth

Phenytoin-induced gingival hyperplasia Hyperplasia of gums induced by direct stimulation of gingival fibroblasts, resulting in ↑ collagen synthesis; PIGO is seen in 10-30% of phenytoin-treated Pts. Cf Phenytoin lymphadenopathy.
References in periodicals archive ?
Maita, "Increased bFGF level in the serum of patients with phenytoin-induced gingival overgrowth," Journal of Clinical Periodontology, vol.
Bolger et al described a case of pronounced phenytoin-induced gingival overgrowth causing glossoptosis and subsequent airway obstruction in a child.
Previous studies demonstrated that CTGF expression is elevated in phenytoin-induced gingival overgrowth tissues, but not in CyA or nifedipine-induced gingival overgrowth.