phenylthiohydantoin


Also found in: Acronyms.

phen·yl·thi·o·hy·dan·to·in (PTH),

(fen'il-thī'ō-hī-dan'tō-in),
The compound formed from an amino acid in the Edman method of protein degradation, in which phenylisothiocyanate reacts with the amino moiety of the N-terminal amino acid to form a phenylthiocarbamoyl peptide or protein, on which weak acids act to release the phenylthiohydantoin containing the N-terminal amino acid.

phen·yl·thi·o·hy·dan·to·in

(fen'il-thī'ō-hī-dan'tō-in)
The compound formed from an amino acid in the Edman method of protein degradation, in which phenylisothiocyanate reacts with the amino moiety of the N-terminal amino acid to form a phenylthiocarbamoyl peptide or protein, on which weak acids act to release the phenylthiohydantoin containing the N-terminal amino acid.