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a nonsteroidal antiinflammatory drug administered orally in the short-term treatment of severe rheumatoid disorders unresponsive to less toxic agents. It is given for periods of less than one week because it can cause aplastic anemia and agranulocytosis.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
phenylbutazoneTherapeutics An NSAID tightly bound to plasma proteins. See NSAIDs.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
phenylbutazoneA non-steroidal anti-inflammatory drug (NSAID) once widely used but now available for use in hospitals only because of its tendency to cause HEART FAILURE from fluid retention and severe blood disorders. It is used, under specialist supervision, in cases of ANKYLOSING SPONDYLITIS.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005