phentolamine


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phentolamine

 [fen-tol´ah-mēn]
a potent alpha-adrenergic blocking agent that blocks the hypertensive action of epinephrine and norepinephrine and most responses of smooth muscles that involve alpha-adrenergic receptors. Its mesylate salt is used intravenously or intramuscularly to prevent and treat hypertension occurring before and during surgery for pheochromocytoma and is also used intravenously to prevent and treat cutaneous necrosis and sloughing when extravasation of norepinephrine occurs after intravenous administration.

phentolamine

(fĕn-tŏl′ə-mēn′)
n.
An alpha-blocker, C17H19N3O, used especially in the diagnosis and treatment of pheochromocytoma.

phentolamine

[fentol′əmēn]
an alpha1-adrenergic receptor blocker.
indications It is prescribed in the control of symptoms of pheochromocytoma before and during surgery and for dermal necrosis and sloughing after extravasation of parenteral drugs with alpha-adrenergic effects (e.g., norepinephrine, epinephrine, dopamine).
contraindications History of myocardial infarction, angina, coronary artery disease, cerebrovascular disease, renal impairment, or known hypersensitivity to this drug prohibits its use.
adverse effects Among the more serious adverse effects are tachycardia, cardiac arrhythmias, anginal pain, and hypotension.

phentolamine

An alpha-ADRENERGIC BLOCKING DRUG used in the treatment of PHAEOCHROMOCYTOMA. A brand name is Rogitine.

phentolamine

a potent α-adrenergic blocking agent; it blocks the hypertensive action of epinephrine and norepinephrine and most responses of smooth muscles that involve α-adrenergic cell receptors. Its hydrochloride and mesylate salts are used in the diagnosis of hypertension due to pheochromocytoma.
References in periodicals archive ?
16] (2005) 42% of patients with erectile dysfunction met criteria for a comorbid psychiatric disorder, 33% reported depressive symptoms, 21% met criteria for an anxiety disorder Uebel and Schmidt [15] (2007) No significant difference between phentolamine and chlorpromazine, or side-effects reported Alexander et al.
Furthermore, the inability of propranolol, phentolamine, atropine and nicotine desensitization to inhibit the schisandrin responses suggested that the relaxant effect was mediated by inhibitory non-adrenergic non-cholinergic (NANC) transmitters released from the enteric nerves.
Use of phentolamine to prevent necrosis due to levarterenol.
Phentolamine mesylate, chemical formula C17H19N30-CH4S03, is a nonselective alpha-adrenergic antagonist.
Papaverine (15-60 mg) and phentolamine (Regitine--mostly used in the combination Trimix preparation--dose of 0.
To examine other potential interferences, we added the following substances and drugs to plasma or urine samples containing 10 [micro]mol/L sulphide: D-arginine (100 [micro]mol/L), L-aspartic acid (100 [micro]mol/L), L-glutamic acid (100 [micro]mol/L), L-glycine (100 [micro]mol/L), L-tyrosine (100 [micro]mol/L), L-threonine (100 [micro]mol/L), L-valine (100 [micro]mol/L), perphenazine (14 [micro]mol/L), lidocaine hydrochloride (10 [micro]mol/L), megimide (16 [micro]mol/L), haloperidol (13 [micro]mol/L), phentolamine methanesulfonate (26 [micro]mol/L), promethazine hydrochloride (10 [micro]mol/L), anisodamine hydrochloride (30 [micro]mol/L), glyphylline (40 F.
Oral phentolamine and female sexual arousal disorder: A pilot study.
Oral phentolamine, a nonselective alpha-blocker, has been used successfully for facilitating erections and treating men with ED (32-35).
Other common drugs that can provoke similar symptoms are aspirin, nonsteroidal anti-inflammatory drugs, beta blockers (oral and ophthalmic), bromocriptine, estrogens, oral contraceptives, prazosin, methyladopa, phentolamine, guanethidine, reserpine, and tricyclic antidepressants.
By blocking alpha-receptors on the smooth muscle cells with drugs like phentolamine (Regitine, Vasomax, mentioned on page 136), contraction of the smooth muscle cells can be prevented or at least reduced, allowing an erection to persist longer.
OPOs should not be guided by a blanket policy on whether or when to use heparin and phentolamine - two drugs used to enhance organ quality before being recovered from a patient.
He is likely to undergo a final set of injections next month with the powerful circulatory drug phentolamine, which improves blood flow and speeds up nerve regeneration.