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A class of major tranquilizers used to treat psychotic illnesses such as schizophrenia. They have neuroleptic and antiemetic effects. Among the most commonly used agents in this class are chlorpromazine, haloperidol, prochlorperazine, and thioridazine. Side effects of these drugs include dystonic reactions, tardive dyskinesia, seizures, and sedation. See: neuroleptic
Medical Dictionary, © 2009 Farlex and Partners
phenothiazinesAn important group of drugs derived from a molecule with a three-ring structure in which two benzene rings are linked by a sulphur and a nitrogen atom. They are widely used to treat serious mental (psychotic) illness and to relieve severe nausea and vomiting. Phenothiazines are divided into three groups. Group I contains drugs such as chlorpromazine (Largactil), methotrimeprazine (Nozinan) and promazine. Group II includes thioridazine (Melleril), pericyazine (Neulactil) and pipothiazine (Piportil Depot). And group III contains prochlorperazine (Stemetil, Buccastem), perphenazine (Fentazin), fluphenazine (Modicate, Moditem, Motival), trifluoperazine (Stelazine) and amitriptyline (Triptafen).
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005