phenothiazine


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Related to phenothiazine: phenothiazine derivatives

phenothiazine

 [fe″no-thi´ah-zēn]
any of a group of having a similar tricyclic structure and acting as potent dopaminergic and alpha-adrenergic blocking agents, as well as having hypotensive, antispasmodic, antihistaminic, analgesic, sedative, and antiemetic activity.

phe·no·thi·a·zine

(fē'nō-thī'ă-zēn),
A compound formerly used extensively for the treatment of intestinal nematodes in animals; without central nervous system depressant activity itself, it serves as the parent compound for synthesis of a large number of antipsychotic compounds, including chlorpromazine, thioridazine, perphenazine, and fluphenazine.
Synonym(s): thiodiphenylamine

phenothiazine

/phe·no·thi·a·zine/ (fe″no-thi´ah-zēn) any of a group of antipsychotic agents having a similar tricyclic structure and acting as potent alpha-adrenergic and dopaminergic blocking agents, as well as having hypotensive, antispasmodic, antihistaminic, analgesic, sedative, and antiemetic activity..

phenothiazine

(fē′nō-thī′ə-zēn′, -nə-)
n.
1. A yellow organic compound, C12H9NS, used in insecticides, livestock anthelmintics, and dyes.
2. Any of a group of drugs derived from this compound and used in the treatment of psychiatric disorders, such as schizophrenia.

phenothiazine

[fē′nōthī′əzēn]
a yellow to green crystalline compound that is a source of dyes and is used in veterinary medicine to treat infestations of threadworms and roundworms. It is too toxic for human use, but derivatives of phenothiazine are used in antipsychotic and antihistamine medications. See also phenothiazine derivatives.

phenothiazine

A class of antipsychotics and tranquilizers–eg, chlorpromazine, compazine, prochlorperazine, thioridazine, thorazine, possibly used as an antiemetic

phenothiazine

the first broad-spectrum veterinary anthelmintic and the market leader in all agricultural animals for many years. Now largely superseded by more efficient compounds. Used now only in horses. Not recommended for use in pregnant mares because of the fear of causing abortion. Its principal use is in mixtures with piperazine and in small daily doses to inhibit egg-laying by resident worms. It must be supported by regular dosing at full dose rates. The name is also used to denote a group of major tranquilizers resembling phenothiazine in molecular structure.
References in periodicals archive ?
Thioridazine, which is a phenothiazine, may cause retinitis pigmentosa in high doses and visual impairment related to this.
Prediction of improvement in schizophrenia under four phenothiazines.
They concluded that many medications, particularly the antihistamines and phenothiazines, are safe and effective for the treatment of varying degrees of nausea and vomiting (Am.
Phenothiazine (98% +) as the inhibitor was also supplied from Aldrich Chemical Co.
11) Wood et al compared antihistamines to phenothiazines, anticholinergics, sympathomimetics, and various combinations.
Pain Medications to Use and Avoid with Older Adults Type of Drug Preferred Avoid Opioids Acetaminophen-Codeine Pentazocine (Talwin [R]) phosphate (Tylenol Meperidine (Demerol [R]) with codeine [R]) Oxycodone Propoxyphene (Darvon-N [R]) (Oxycontin [R]) Hydromorphone (Dilaudid [R]) NSAIDs Ibuprofen (Motrin [R]) Indomethacin (Indocin [R]) Salsalate (Salsitab [R]) Piroxicam (Feldene [R]) Diflunisal (Dolobid [R]) Phenylbutazone Acetaminophen (Tylenol [R]) (Cotylbutazones [R]) Adjuvant Trazadone (Desyrel [R]) Aspirin (Bayer [R]) Fluoxetine (Prozac [R]) Amitriptyline (Elavil [R]) Desipramine (Norpramin [R]) Phenothiazine (Thorazine [R])
Drugs that may exacerbate the symptoms of RLS include diphenhydramine, phenytoin, lithium, prochlorperazine, metoclopramide, haloperidol, phenothiazine derivatives (i.
Vomiting ceased after treatment with phenothiazine, and nausea and cramps resolved the following day.
Phenothiazine, an effective and economical drug for removing many worm parasites from horses, swine, sheep, goats, and poultry, was discovered, saving millions of dollars and untold harm to livestock.
The calcium carbonate compound was denoted as PPCC, the talc compound as PPT, the clay montmorillonite compound as PPC, and the phenothiazine nucleating polypropylene as PPPT.
Her honours project was supervised by Robert McDonald, FCIC, and involved the synthesis and characterization of phenothiazine derivatives as potential inhibitors of cholinesterase for the treatment of Alzheimer's Disease.