phenobarbitone


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Related to phenobarbitone: phenytoin

phenobarbitone

(fē′nō-bär′bĭ-tōn′)
n. Chiefly British
Phenobarbital.

phenobarbitone

Phenobarbital, a BARBITURATE drug now used mainly as an ANTICONVULSANT. Phenobarbitone is no longer used as a sedative or HYPNOTIC. The drug is on the WHO official list. A brand name is Luminal.

Patient discussion about phenobarbitone

Q. What are the Brands of Sodium-phenobarbitone drug in Bangladesh?

A. maybe this link will help-
http://www.medindia.net/doctors/drug_information/phenobarbitone.htm

if not- i recommend asking an Indian pharmacist..

More discussions about phenobarbitone
References in periodicals archive ?
In our study, we compared the neem root extract with that of a standard drug phenobarbitone and diazepam in MES- and PTZ-induced convulsions, respectively.
Phenobarbitone induced cytosolic cytoprotective mechanisms that offset increases in NADPH cytochrome P450 reductase activity in menadione-mediated cytotoxicity.
Phenobarbitone is generally regarded as the most commonly prescribed antiepileptic medication (AED) in developing countries (15,16,20) on accounts of its being 5, 15 and 20 times cheaper than phenytoin, carbamazepine and sodium valproate respectively (13).
The clinical picture of phenobarbitone induced gingival enlargement shows the gingival tissues around the teeth inflamed and enlarged.
Gupta, "Pharmacokinetic and pharmacodynamic interactions of valproate, phenytoin, phenobarbitone and carbamazepine with curcumin in experimental models of epilepsy in rats," Pharmacology Biochemistry and Behavior, vol.
Dose (a) Neurotoxicity ([mu]mol/kg) scPTZ MES (b) 6a 750 16 -- 0/6 6b 667 50 66 (c) 0/6 6c 680 50 -- 2/6 6d 718 100 16 0/6 6e 718 83 50 0/6 6f 684 100 _ (c) 0/6 6g 972 50 -- 0/6 6h 616 83 16 (c) 0/6 6i 645 100 16 (c) 0/6 6j 586 66 16 0/6 6k 520 50 16 1/6 6l 818 100 16 (c) 0/6 6m 565 16 16 2/6 6n 814 100 _ (c) 0/6 6o 662 66 16 0/6 6p 636 100 _ (c) 0/6 Phenytoin 159 -- 100 ND Phenobarbitone 108 100 -- ND (a) Doses were administered i.p.
Values represent the onset of sleep and duration of sleep (in min) after treatment with normal saline (10 ml/kg), ZEO (200, 300 and 400) or bromazepam (5 mg/kg) and then all groups were treated with phenobarbitone (35 mg/kg).
[4] gave prophylactic phenobarbitone to infants with perinatal asphyxia and could not demonstrate a superior outcome compared with untreated infants in terms of seizures or mortality.
Children with refractory convulsions were given IV phenobarbitone 20mg/kg stat, followed by 5mg/kg once a day dose.
Profhylactic role of single dose phenobarbitone is preventing convulsion in cerebral malaria.