found no effect of injection velocity on cough incidence.11 Several methods are tried to prevent fentanyl induced cough.3,4,11-13 But, in literature there is no data about the effect of pheniramine
maleat on fentanyl induced cough.
Comparison of Histamine-induced Contractility after Pheniramine
Pretreatment between Hirschsprung's and non-Hirschsprung's Cases
maleate was procured from Aventis Pharma Limited (Bangalore, India).
Premedication with hydrocortisone and pheniramine
maleate was given routinely to all the patients.
It revealed a higher affinity toward [H.sub.1] receptor compared to [H.sub.2] and [H.sub.3] histaminergic receptors and its selectivity toward H1 receptor was superior to other ocular antihistamines such as ketotifen, pheniramine
, and levocabastine.
With its active antihistamine (pheniramine
maleate) and a decongestant, OcuHist temporarily relieves itching and redness of the eyes due to pollen, ragweed, grass, animal hair and dander, according to a spokesman.
Miscellaneous drugs include vaccines such as tetanus toxoid (n = 07; 1.96%), nutritional supplements such as arginine (n = 05; 1.40%), Antihistaminics such as cetirizine and pheniramine
maleate (n = 04; 1.12%), local anesthetic such as lignocaine (n = 03; 0.84%), and corticosteroids such as dexamethasone (n = 02; 0.56%) were prescribed (Table 2).
Meloxicam (b) (0.5 mg/kg b.wt., IM) and Inj Pheniramine
maleate (Anistamin (b) 10 ml, IM) daily for five days and Inj.
Overall, cetirizine (59.2%) was the most commonly prescribed [H.sub.1] antihistamine drug as monotherapy, and pheniramine
+ cetirizine (16.4%) was the most commonly prescribed antihistaminic combination (Table 2).
Premedication consists of Dexamethasone 8 mg IV, Pheniramine
IV, Ranitidine 50 mg IV and a 5HT3-receptor antagonist as antiemetic.
5% DNS @ 1 liter along with antibiotic (Enrogil (a)), analgesic (Melonex (b)) and antihistaminic (Pheniramine
maleate (c)) were administered for five days in prescribed doses.