phenethyl isothiocyanate

phenethyl isothiocyanate

Clinical nutrition An organosulfur compound derived from Alium spp–garlic, onions–which inhibits nitrosamine-induced esophagus and lung CAs, and prevents DNA adduct formation in animals. See Garlic.
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One is another mouse study by Tin Oo Khor et al 2006 published in the journal Cancer titled 'Combined Inhibitory Effects of Curcumin and Phenethyl Isothiocyanate on the Growth of Human PC-3 Prostate Xenografts in Immunodeficient Mice' , in which the researchers grew prostate cancer tumors in mice and tested various substances, including curcumin, to test how they affected the tumors.
Some isothiocyanates, such as allyl isothiocyanate, benzyl isothiocyanate (BITC), phenethyl isothiocyanate (PEITC), and sulforaphane (SFN), have been shown to have substantial chemopreventive activity against various human malignancies (7).
Phenethyl Isothiocyanate. Phenethyl isothiocyanate (PEITC) is a member of isothiocyanate distributed as gluconasturtiin in some cruciferous plants including broccoli, cabbage, cauliflower, horseradish, and watercress [105].
In fact, medical research is investigating how a plant compound found in watercress - PEITC (phenethyl isothiocyanate) - may have the ability to suppress breast cancer cell development by "turning off " a signal in the body and thereby starving the growing tumour of essential blood and oxygen.
In fact, medical research is investigating how a plant compound found in watercress - PEITC (phenethyl isothiocyanate) - may have the ability to suppress breast cancer cell development by 'turning off' a signal in the body and thereby starving the growing tumour of essential blood and oxygen.
Kong, "Molecular targets of dietary phenethyl isothiocyanate and sulforaphane for cancer chemoprevention," The AAPS Journal, vol.
Inhibitory effect of phenethyl isothiocyanate against benzo[a] pyrene-induced rise in CYP1A1 mRNA and apoprotein levels as its chemopreventive properties.
Dietary isothiocyanates include sulforaphane, phenethyl isothiocyanate (PEITC), benzyl-isothiocyanate, and 6-methylsulfinylhexyl-isothiocyanate (Figure 6).
Phenethyl isothiocyanate (PEITC), a natural metabolite of glucosinolates from watercress, has been found, for example, to down-regulate androgen receptors, minimizing stimulation of prostate cancer by testosterone.
Washington, Aug 3 ( ANI ): A new study by researchers, including one of Indian origin, has found that the natural plant compound phenethyl isothiocyanate (PEITC) hinders the development of mammary tumours in a mouse model with similarities to human breast cancer progression.
Phenethyl isothiocyanate sensitizes androgen-independent human prostate cancer cells to docetaxel-induced apoptosis in vitro and in vivo.
(2007) observed in vitro that phenethyl isothiocyanate (PEITC) binds covalently to cellular proteins and induces apoptosis in cancer cell lines.