phenethyl isothiocyanate

phenethyl isothiocyanate

Clinical nutrition An organosulfur compound derived from Alium spp–garlic, onions–which inhibits nitrosamine-induced esophagus and lung CAs, and prevents DNA adduct formation in animals. See Garlic.
References in periodicals archive ?
They found that a metabolite of phenethyl isothiocyanate (PEITC) that is abundant in watercress inhibits the proliferation of prostate cancer cells and their ability to form tumors.
Washington, Aug 3 ( ANI ): A new study by researchers, including one of Indian origin, has found that the natural plant compound phenethyl isothiocyanate (PEITC) hinders the development of mammary tumours in a mouse model with similarities to human breast cancer progression.
Phenethyl isothiocyanate sensitizes androgen-independent human prostate cancer cells to docetaxel-induced apoptosis in vitro and in vivo.
In the lab, a compound called phenethyl isothiocyanate, found in cruciferous veggies including broccoli, cabbage and cauliflower, stopped ovarian cancer cells from spreading.
Betacarotene, as well as chemicals with nasty-sounding names like phenethyl isothiocyanate (PEITC), found in cauliflower and broccoli, and ellagic acid, found in strawberries and other fruits and vegetables, may help defend our bodies against carcinogens.
Phenethyl isothiocyanate (PEITC), a natural metabolite of glucosinolates from watercress, has been found, for example, to down-regulate androgen receptors, minimizing stimulation of prostate cancer by testosterone.
Furthermore, we show that cells with p53 mutations are more sensitive to cytotoxicity induced by phenethyl isothiocyanate (PEITC) than those with the wild-type protein.
Effects of indole-3-carbinol and phenethyl isothiocyanate on colon carcinogenesis induced by azoxymethane in rats.
Prevention of cigarette smoke-induced lung tumors in mice by budesonide, phenethyl isothiocyanate, and N-acetyl cysteine.
4 mg/kg diet), phenethyl isothiocyanate (PEITC, 1,000 mg/kg diet), and N-acetyl cysteine (NAC, 1,000 mg/kg body weight) were administered orally according to various protocols.
3-7) Watercress is also an exceptionally rich dietary source of nasturtiin, the precursor of phenethyl isothiocyanate (PEITC).
Most recently, scientists have shown that a particular cruciferous vegetable compound known as phenethyl isothiocyanate (PEITC) directly inhibits a tumor's ability to supply itself with blood.