1 -100 [micro]M MA and NGS for 60 min at 37[degrees]C after the addition of 80 pM phenacetin
as a selective CYP1A substrate and 50 [micro]M bupropion as a selective CYP2B6 substrate.
was discontinued in the early 1980s due to concerns about nephropathy and carcinogenesis.
Different roles for phenacetin
and paracetamol in cancer of the kidney and renal pelvis.
and proteinuria--a disease entity caused by environmental disruption which threatens health of man in Japanese].
Known and probable reproductive and Known and probable carcinogens developmental toxins Acrylamide Lithium carbonate Coal tar Dibutyl phthalate Ethylacrylate Toluene Formaldehyde Lead acetate HC Blue 2 Potassium dichromate Lead acetate Butoxyethanol Phenacetin
Dimethicone triethanolamine Phenolphthalein Diethanolamine Phenylphenol Cetyl phosphate Potassium dichromate Diglycol-cyclohexanedimethanol Progesterone Selenium sulfide
, and non-steroidal anti-inflammatory agents like naprosyn and indocin--or infection such as pyelonephritis).
content=findings_ingreds_of_concern#begin Top ingredients of concern in Skin Deep: Known and probable carcinogens Acrylamide Coal tar Ethylacrylate Formaldehyde HC Blue 2 Lead acetate Phenacetin
Phenolphthalein Phenylphenol Potassium dichromate Progesterone Selenium sulfide Known and probable reproductive and developmental toxins Lithium carbonate Dibutyl phthalate Toluene Lead acetate Potassium dichromate Butoxyethanol Dimethicone triethanolamine Diethanolamine Cetyl phosphate Diglycol-cyclohexanedimethanol
Even though many cat owners are aware of the danger of acetaminophen (also known as paracetamol in Britain; phenacetin
is another source of acetaminophen), it's easy to forget that it is often included in many other over-the-counter medications.
German chemists produced three antipyretics in the late 1880s known as Atipyrene, Antifebrin, and Phenacetin
In the 1890s, a popular nonprescription painkiller and headache remedy called phenacetin
was regularly smuggled into the United States from Canada in large quantities.
Hereditary HbM NADH-MetHb reductase deficiency Acquired Medications Amyl nitrite Benzocaine Dapsone Lidocaine Nitroglycerin Nitroprusside Phenacetin
Phenazopyridine Prilocaine Quinones (chloroquinone, primaquine) Sulfonamides (sulfanilamide, sulfathiazide, sulfapyridine, sulfamethoxazole) Chemical agents Aniline dye derivatives (shoe dyes, inks) Butyl nitrite Chlorobenzene Nitrate-containing foods Isobutyl nitrite Naphthalene Nitrophenol Nitrous gases Silver nitrate Trinitrotoluene Well water nitrates Pediatric Decreased NADH-MetHb reductase activity (<4 months of age) Associated with low birth weight, prematurity, dehydration, acidosis, and diarrhea Table 3.