phase one study

phase one study

a clinical trial to assess the risk that may arise from administering a new treatment modality. A phase two study evaluates the clinical effectiveness of the new modality, and a phase three study compares its effectiveness with that of the best existing treatment.
References in periodicals archive ?
The vaccine, based on a genetically modified cold virus, was developed in the lab of Zhou Xing, professor of pathology and molecular medicine and the McMaster Immunology Research Centre, who co-led the phase one study with Dr.
Galapagos completed a phase one study of its SARM drug candidate in healthy volunteers, which showed positive results in terms of exposure and tolerability.
A similar Phase One study looking at brain cancer is already under way in the US.
It was concluded as part of the JIP Phase One study that the successful completion of this program would confirm the suitability of the Subsea 7/Flowserve Multiphase Pumping System Package for installations in water depths to 4,920 feet (1,500 meters).
A successful phase one study which compared Maelor's micelle propofol with AstraZeneca's established Diprivan product in inducing general anaesthesia concluded that there were no clinical or statistically significant differences between the two formulations.
Approximately 10 patients will be enrolled in the phase one study of the Envoy System, with an expanded phase two study to commence shortly after pending FDA approval, said Doug Hoag, spokesman for St.
The Phase One study successfully demonstrated the proof-of-concept fiberization of the Hedman serpentine ore.
In a phase one study, CTLA-Ig prevented the development of GVHD in 8 of 11 evaluable patients receiving a SCT for leukemia or other hematopoeitic malignancies (New England Journal of Medicine, 1999, 340 (22) 1704-1714).
In addition the study will serve as a phase one study for the company's US FDA IDE filing.
The 10-week, double-blind phase one study was conducted at New Zealand's Otago University in conjunction with AgResearch Invermay -- an agricultural research organization owned by the New Zealand government.
Food and Drug Administration (FDA)-approved Investigational Device Exemption (IDE) Phase One study using the ZEUS Robotic Surgical System.