phase one study

phase one study

a clinical trial to assess the risk that may arise from administering a new treatment modality. A phase two study evaluates the clinical effectiveness of the new modality, and a phase three study compares its effectiveness with that of the best existing treatment.
References in periodicals archive ?
Enrollment in the dose escalation part of the Phase one study of MGA012 has been completed and the molecule is presently being assessed as monotherapy across four solid tumour types in the dose expansion portion of the study.
The vaccine, based on a genetically modified cold virus, was developed in the lab of Zhou Xing, professor of pathology and molecular medicine and the McMaster Immunology Research Centre, who co-led the phase one study with Dr.
A similar Phase One study looking at brain cancer is already under way in the US.
In a phase one study of young college students (the product of the teacher-librarian's information literacy efforts in the K-12 arena), Alison Head and Michael Eisenberg (2009) asked what problems these young adults faced in doing research assignments in college.
It was concluded as part of the JIP Phase One study that the successful completion of this program would confirm the suitability of the Subsea 7/Flowserve Multiphase Pumping System Package for installations in water depths to 4,920 feet (1,500 meters).
A successful phase one study which compared Maelor's micelle propofol with AstraZeneca's established Diprivan product in inducing general anaesthesia concluded that there were no clinical or statistically significant differences between the two formulations.
Of the 148 responding, 65 (44 percent) sent national materials, and 61 of the 65 (94 percent) sent national materials that related to the confidence swindles in the Phase One study.
The specific aims of the study included: (1) to find out about the user population in terms of who uses it, their extent and purpose of use, what features of the Schoolsnet were used, and what was the level of Internet use from Schoolsnet; (2) to determine what influences a person's "three phases of use of the Schoolsnet" (exploration, discovery, and promotion); (3) to explore how the curriculum content and features of the Schoolsnet have enhanced the learning process; (4) to study how physical and environmental features affect the use of Schoolsnet; (5) to determine what is needed for the future, especially in terms of services, content, and charges; and (6) to identify what has changed since the phase one study.
The company is now poised to begin its phase one study of GBR 1342, a humanised monoclonal antibody for the treatment of multiple myeloma.
The Phase One study successfully demonstrated the proof-of-concept fiberization of the Hedman serpentine ore.
M2 EQUITYBITES-April 5, 2017-Atossa Genetics completes enrolment of six cohorts for Phase one study of endoxifen breast cancer drug