phase II trial


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Related to phase II trial: clinical test, double-dummy

phase II trial

, phase 2 trial
A clinical trial to determine the potential effectiveness of a new drug. Generally, if at least 20% of the study subjects respond positively to it, e.g., achieve a 50% reduction in the total size of their measurable tumor, the new therapy will receive further testing. Another crucial statistic is the duration of response. Short-term responses may mean little in terms of survival; long-term responses indicate that the drug is benefiting some patients.
See also: trial
References in periodicals archive ?
Dr Eugene Braunwald, chairman of the TIMI Study Group said: "We are very interested in learning in this Phase II trial whether BB-10153 can successfully lyse clots and provide an acceptable safety profile in terms of bleeding risk.
Despite known side effects in animals, neither Sher, Biron, nor Stevenson can speculate what happened to the kidney cancer patients in the Genetics Institute's phase II trial.
Investigation of patient records for the DAD2000 trial, Immune Network's international Phase II trial of dapsone in Alzheimer disease, revealed no adverse findings as observed in the halted Canadian Phase I trial.