(22) detected the TLR4 expression in astrocytes of pharmacoresistant
patients with TLE (n=26), and they discovered that a higher expression of TLR4 was correlated with higher seizure frequency (r=0.408; P=0.02).
A multi-site, observational study of transcranial magnetic stimulation for patients with pharmacoresistant
major depressive disorder: durability of benefit over a one-year follow-up period.
The early onset of seizures, larger unilateral lesions or bilateral disease, are risk factors for developing pharmacoresistant
epilepsy and intellectual impairment [5-7].
The prevalence of epilepsy and pharmacoresistant
epilepsy in adults: a population-based study in a Western European country.
Ketogenic diet effects on 52 children with pharmacoresistant
epileptic encephalopathy: A clinical prospective study.
Previously, Mark was the Chief Medical Officer at Neuronetics, Inc., where he was responsible for the development and approval of the NeuroStar transcranial magnetic stimulation system for the treatment of pharmacoresistant
depression, and Medical Director at Lilly Research Labs where he was responsible for the development of CNS drugs from early phase to post-market commercialization and oversaw the development and approval of Cymbalta for major depression.
Ictal and interictal data were obtained from five patients with pharmacoresistant
focal onset epilepsy undergoing some presurgical evaluations.
Farisse et al., "Predictive value of brain perfusion SPECT for rTMS response in pharmacoresistant
depression," European Journal of Nuclear Medicine and Molecular Imaging, vol.
Turaga et al., "Retention of perampanel in adults with pharmacoresistant
epilepsy at a single tertiary care center," Epilepsy & Behavior, vol.
Genetic association study of the HLA class II alleles DRBl, DQAl, and DQBl in patients with pharmacoresistant
temporal lobe epilepsy associated with mesial hippocampal sclerosis.
Aim: To evaluate the value of vagal nerve stimulation (VNS) in improving the quality of life, seizure frequency and mood in children with pharmacoresistant
Initially, a ketogenic diet proved to be an effective therapy in pharmacoresistant