pharmacokinetic


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phar·ma·co·ki·net·ic

(far'mă-kō-ki-net'ik),
Relating to the disposition of drugs in the body (that is, their absorption, distribution, metabolism, and elimination).

pharmacokinetic

adjective Referring to pharmacokinetics, the science that studies the processes of bodily absorption, distribution, metabolism and excretion (ADME) of compounds and medicines.

phar·ma·co·ki·net·ic

(fahr'mă-kō-ki-net'ik)
Relating to the disposition of drugs in the body (i.e., their absorption, distribution, metabolism, and elimination).

phar·ma·co·ki·net·ic

(fahr'mă-kō-ki-net'ik)
Relating to disposition of drugs in body (i.e., absorption, distribution, metabolism).
References in periodicals archive ?
Keywords: Atorvastatin, HPLC, Hyperlipidemia, Pharmacokinetic studies, Statins.
Propofol was stopped during surgery after the end of the infusion period with the first pharmacokinetic model.
Results: The pharmacokinetic profiles indicated that the glucuronide conjugates of icaritin were the principle circulating metabolites and that total icaritin accounted for ~99% of prenylflavonoid exposure after administration of EWH-derived materials to rats.
To estimate the pharmacokinetic parameters of methotrexate in the investigated population, the following models were used to describe the intersubject variability in cleareance:
Pharmacokinetic Analysis: The pharmacokinetic parameters of ketoprofen in buffalo calves were analyzed by computer based pharmacokinetic software, APO pharmacological analysis MW /PHARM version 3.
According to the known pharmacokinetic parameters of busulfan, the values for the maximum and minimum concentrations increase during the first 3 doses.
Taking 80 mg of oral ziprasidone twice daily with a meal of at least 500 kcal resulted in a mean trough level of 70 ng/mL and ensured linear pharmacokinetics.
Neuren's Phase 2a clinical trial investigated the safety, tolerability and pharmacokinetics of a 4-hour infusion of Glypromate(R) in 33 cardiac surgery patients.
Pharmacokinetics of topical Ciprodex otic suspension in pediatric and adolescent patients after tympanostomy tube surgery.
acslXtreme[R] Pharmacokinetic OPTIMUM modeling software gives drug developers and risk assessors robust parameter estimation, model optimization, sensitivity analysis, and Monte Carlo analysis capabilities that are critical to solving many complex applied mathematical problems and for optimizing model parameters against experimental data.
First, in light of the pharmacokinetic properties of phthalates, the reported blood levels are very high when compared to more recent exposure information, and, second, toxicologic evidence shows that phthalates do not act like estrogens under in vivo conditions, nor do they affect female sexual development and maturation in rodents.