Keywords: Atorvastatin, HPLC, Hyperlipidemia, Pharmacokinetic
Propofol was stopped during surgery after the end of the infusion period with the first pharmacokinetic
Results: The pharmacokinetic
profiles indicated that the glucuronide conjugates of icaritin were the principle circulating metabolites and that total icaritin accounted for ~99% of prenylflavonoid exposure after administration of EWH-derived materials to rats.
To estimate the pharmacokinetic
parameters of methotrexate in the investigated population, the following models were used to describe the intersubject variability in cleareance:
Analysis: The pharmacokinetic
parameters of ketoprofen in buffalo calves were analyzed by computer based pharmacokinetic
software, APO pharmacological analysis MW /PHARM version 3.
According to the known pharmacokinetic
parameters of busulfan, the values for the maximum and minimum concentrations increase during the first 3 doses.
Taking 80 mg of oral ziprasidone twice daily with a meal of at least 500 kcal resulted in a mean trough level of 70 ng/mL and ensured linear pharmacokinetics
Neuren's Phase 2a clinical trial investigated the safety, tolerability and pharmacokinetics
of a 4-hour infusion of Glypromate(R) in 33 cardiac surgery patients.
of topical Ciprodex otic suspension in pediatric and adolescent patients after tympanostomy tube surgery.
OPTIMUM modeling software gives drug developers and risk assessors robust parameter estimation, model optimization, sensitivity analysis, and Monte Carlo analysis capabilities that are critical to solving many complex applied mathematical problems and for optimizing model parameters against experimental data.
First, in light of the pharmacokinetic
properties of phthalates, the reported blood levels are very high when compared to more recent exposure information, and, second, toxicologic evidence shows that phthalates do not act like estrogens under in vivo conditions, nor do they affect female sexual development and maturation in rodents.