pharmacodynamics


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pharmacodynamics

 [fahr″mah-ko-di-nam´iks]
the study of the biochemical and physiological effects of drugs and the mechanisms of their actions, including the correlation of their actions and effects with their chemical structure. adj., adj pharmacodynam´ic.

phar·ma·co·dy·nam·ics

(far'mă-kō-dī-nam'iks),
The study of uptake, movement, binding, and interactions of pharmacologically active molecules at their tissue site(s) of action.
[pharmaco- + G. dynamis, force]

pharmacodynamics

(fär′mə-kō′dī-năm′ĭks)
n. (used with a sing. verb)
The study of the action or effects of drugs on living organisms.

phar′ma·co′dy·nam′ic adj.
phar′ma·co′dy·nam′i·cal·ly adv.

pharmacodynamics

The study of the biochemical and physiological interactions between therapeutic agents and living systems.

phar·ma·co·dy·nam·ics

(fahr'mă-kō-dī-nam'iks)
The study of uptake, movement, binding, and interactions of pharmacologically active molecules at their tissue site(s) of action.
[pharmaco- + G. dynamis, force]

phar·ma·co·dy·nam·ics

(fahr'mă-kō-dī-nam'iks)
Study of uptake, movement, binding, and interactions of pharmacologically active molecules at their tissue site(s) of action.
[pharmaco- + G. dynamis, force]
References in periodicals archive ?
Timing May Influence the Pharmacodynamics of Atropine as Pre-Medication.
A literature search was performed in the PubMed/MEDLINE database looking for clinical trials, journal articles or reviews available in full-text, written in Spanish or English languages, published from January 1962 to July 2015, including the keywords: pharmacodynamics (PD), pharmacokinetics (PK), antifungals, candidiasis, and aspergillosis.
Blood samples were collected during the first 24 hours for pharmacokinetic measurements and at 2, 3, and 4 weeks for pharmacodynamic determinations.
In this bioassay, we compared the pharmacodynamics of capsaicin, natural capsaicinoids, and piperine and studied the effect of desensitization after repeated exposure and the effect of the specific TRPV1 antagonist, SB366791.
Jude has focused on the pharmacokinetics, pharmacodynamics, and pharmacogenomics of anticancer agents in children.
In addition, the study will evaluate the pharmacokinetics and pharmacodynamics of inhaled Ostabolin-C, as well as the effect of inhaled Ostabolin-C on serum markers of bone formation and resorption.
Knowing the pharmacodynamics and pharmacokinetics of antimicrobial agents is essential for these drugs to be used correctly, and a good overview of these mechanisms is also provided in these beginning chapters.
Sex differences in pharmacokinetics and pharmacodynamics. Annu Rev Pharmacol Toxicol.
Works both on botany and agriculture, and on chemistry, pharmacodynamics and usage have been considered.
This leading-edge technology reduces the process workflow in proteomics analysis, and enables more accurate studies in protein expression kinetics and pharmacodynamics," said Neil Cook, chief scientific officer, PerkinElmer Life and Analytical Sciences.
The 28-day study will evaluate the safety, tolerability and pharmacodynamics of VX-950 when combined with pegylated interferon and ribavirin, two existing approved treatments for HCV infection.
Such HuEPO-L-vFc fusion proteins exhibit extended serum half-life and increased biological activities, leading to improved pharmacokinetics and pharmacodynamics, thus fewer injections will be needed within a period of time.