pharmacodynamics

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pharmacodynamics

[fahr″mah-ko-di-nam´iks]

the study of the biochemical and physiological effects of drugs and the mechanisms of their actions, including the correlation of their actions and effects with their chemical structure. adj., adj pharmacodynam´ic.

phar·ma·co·dy·nam·ics

(far'mă-kō-dī-nam'iks),

The study of uptake, movement, binding, and interactions of pharmacologically active molecules at their tissue site(s) of action.

[pharmaco- + G. dynamis, force]

pharmacodynamics

/phar·ma·co·dy·nam·ics/ (-di-nam´iks) the study of the biochemical and physiological effects of drugs and the mechanisms of their actions, including the correlation of their actions and effects with their chemical structure.pharmacodynam´ic

pharmacodynamics

(fär′mə-kō′dī-năm′ĭks)

n. (used with a sing. verb)

The study of the action or effects of drugs on living organisms.

phar′ma·co′dy·nam′ic adj.

phar′ma·co′dy·nam′i·cal·ly adv.

pharmacodynamics

[-dīnam′iks]

Etymology: Gk, pharmakon, drug, dynamis, power

the study of how a drug acts on a living organism, including the pharmacological response and the duration and magnitude of response observed relative to the concentration of the drug at an active site in the organism.

pharmacodynamics

The study of the biochemical and physiological interactions between therapeutic agents and living systems.

phar·ma·co·dy·nam·ics

(fahr'mă-kō-dī-nam'iks)

The study of uptake, movement, binding, and interactions of pharmacologically active molecules at their tissue site(s) of action.

[pharmaco- + G. dynamis, force]

pharmacodynamics

study of drug effects on living organisms (i.e. what a drug does to the body)

pharmacodynamics,

n the division of pharmacology that studies the effects of drugs and their mechanisms of action in the body.

phar·ma·co·dy·nam·ics

(fahr'mă-kō-dī-nam'iks)

Study of uptake, movement, binding, and interactions of pharmacologically active molecules at their tissue site(s) of action.

[pharmaco- + G. dynamis, force]

pharmacodynamics (fär´məkōdī-nam´iks),

n the science of drug action.

pharmacodynamics

the study of the mechanisms of action of drugs and other biochemical and physiological effects.

References in periodicals archive ?

Because of potential interference of hawthorn with the polyclonal antibody-based serum digoxin immunoassay and competition between hawthorn and digoxin for possible binding to the same site of Na, K adenosine triphosphatase, thus interacting pharmacodynamically with digoxin, it is advisable that a patient receiving digoxin should not take hawthorn.

Interference of hawthorn on serum digoxin measurements by immunoassays and pharmacodynamic interaction with digoxin

To maintain the activity of the fluoroquinolone class, clinicians need to implement an evidence-based approach to antimicrobial selection, particularly a strategy in which the most pharmacodynamically potent fluoroquinolone is matched, on an empiric basis when required, to anticipated bacterial pathogens.

Maintaining fluoroquinolone class efficacy: review of influencing factors. (Perspectives)

Ex-RAD displayed excellent oral bioavailability and pharmacodynamically relevant levels were readily achieved, suggesting that oral delivery of Ex-RAD is feasible.

Onconova Presents Positive Clinical Trial Results for Radiation Injury Protector Ex-RAD[R]

Thus, current drugs may interact pharmacodynamically in ways that are neither understood nor predictable at the present time.

Study of identification and assessment of drug-drug interactions

Drugs may interact pharmacokinetically and pharmacodynamically.

Antidepressants in geriatric patients: reduce the risk of GI bleeding

This intuitive model has not been proven superior to any other model of selecting antidepressants, but it is clinically sound, pharmacodynamically appealing, and supported by case reports.

Achieving the best outcome in treatment of depression. (Research Findings That Are Changing Clinical Practice)

Pharmacokinetic (PK) data reveal plasma levels with oral rigosertib were above the predicted pharmacodynamically active levels.

Onconova Presents Clinical Trial Data for Oral Rigosertib at ASCO Annual Meeting

25) We suggest that you follow SGA guidelines as a default when using mirtazapine--which is pharmacodynamically the most similar to SGAs--and TCAs.

How to control weight gain when prescribing antidepressants: ignoring this side effect can increase medical risk, treatment nonadherence