pharmacodynamics

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pharmacodynamics

[fahr″mah-ko-di-nam´iks]

the study of the biochemical and physiological effects of drugs and the mechanisms of their actions, including the correlation of their actions and effects with their chemical structure. adj., adj pharmacodynam´ic.

phar·ma·co·dy·nam·ics

(far'mă-kō-dī-nam'iks),

The study of uptake, movement, binding, and interactions of pharmacologically active molecules at their tissue site(s) of action.

[pharmaco- + G. dynamis, force]

pharmacodynamics

(fär′mə-kō′dī-năm′ĭks)

n. (used with a sing. verb)

The study of the action or effects of drugs on living organisms.

phar′ma·co′dy·nam′ic adj.

phar′ma·co′dy·nam′i·cal·ly adv.

pharmacodynamics

The study of the biochemical and physiological interactions between therapeutic agents and living systems.

phar·ma·co·dy·nam·ics

(fahr'mă-kō-dī-nam'iks)

The study of uptake, movement, binding, and interactions of pharmacologically active molecules at their tissue site(s) of action.

[pharmaco- + G. dynamis, force]

phar·ma·co·dy·nam·ics

(fahr'mă-kō-dī-nam'iks)

Study of uptake, movement, binding, and interactions of pharmacologically active molecules at their tissue site(s) of action.

[pharmaco- + G. dynamis, force]

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References in periodicals archive ?

Because of potential interference of hawthorn with the polyclonal antibody-based serum digoxin immunoassay and competition between hawthorn and digoxin for possible binding to the same site of Na, K adenosine triphosphatase, thus interacting pharmacodynamically with digoxin, it is advisable that a patient receiving digoxin should not take hawthorn.

Interference of hawthorn on serum digoxin measurements by immunoassays and pharmacodynamic interaction with digoxin

To maintain the activity of the fluoroquinolone class, clinicians need to implement an evidence-based approach to antimicrobial selection, particularly a strategy in which the most pharmacodynamically potent fluoroquinolone is matched, on an empiric basis when required, to anticipated bacterial pathogens.

Maintaining fluoroquinolone class efficacy: review of influencing factors. (Perspectives)

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Thus, current drugs may interact pharmacodynamically in ways that are neither understood nor predictable at the present time.

Study of identification and assessment of drug-drug interactions

Drugs may interact pharmacokinetically and pharmacodynamically. Pharmacokinetic interactions are well understood and represent changes in absorption, distribution, metabolism, and elimination of specific medications.

Antidepressants in geriatric patients: reduce the risk of GI bleeding

This intuitive model has not been proven superior to any other model of selecting antidepressants, but it is clinically sound, pharmacodynamically appealing, and supported by case reports.

Achieving the best outcome in treatment of depression. (Research Findings That Are Changing Clinical Practice)

Ninety-nine patients were treated with an optimized dosing schedule using pharmacodynamically guided dose up-titration: a starting dose of erdafitinib at 8 mg daily, with the possibility to increase the dose to 9 mg daily based on serum phosphate levels.

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(25) We suggest that you follow SGA guidelines as a default when using mirtazapine--which is pharmacodynamically the most similar to SGAs--and TCAs.

How to control weight gain when prescribing antidepressants: ignoring this side effect can increase medical risk, treatment nonadherence