pharmacodynamic


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Related to pharmacodynamic: pharmacokinetic

phar·ma·co·dy·nam·ic

(far'mă-kō-dī-nam'ik),
Relating to drug action.

phar·ma·co·dy·nam·ic

(fahr'mă-kō-dī-nam'ik)
Relating to drug action, particularly at the receptor level.
References in periodicals archive ?
In summary, it provides detailed guidance for companies that wish to develop pharmacodynamic assays to supplement their traditional research supplies or bio-pharmaceutical product development.
that used an in vitro pharmacodynamic model, levofloxacin was less likely than moxifloxacin to select for resistant isolates of S.
In his presentation entitled "Impact of Vehicle Composition on Percutaneous Penetration and Hair Growth Response of a Tri and Hexapeptide Complex," Ignace outlined ProCyte's development of an in vivo pharmacodynamic model.
Pharmacodynamic analyses demonstrate substantial reductions in biomarkers of PI3K and mTOR activity in multiple tumor types.
MLN4924, a Novel NAE Inhibitor, Induces Pharmacodynamic Changes in Blood and Skin
The pharmacodynamic and pharmacokinetic time-profiles of EP42675 followed a parallel pattern, with a low intra and inter subjects variability.
Importantly, these data also suggest that our oral spray may provide earlier therapeutic drug concentrations and a more rapid pharmacodynamic effect, even while administering lower doses of zolpidem.
This work will demonstrate capability for quantification of pharmacodynamic parameters, intracellular concentration and DNA incorporation that may provide robust measures of target cell exposures from circulating doses.
Additionally, a pharmacodynamic assessment of gastrointestinal transit time was included in the study, but the assay did not perform reliably and no conclusions could be drawn.
Using distinct HIF-PH inhibitors with unique pharmacodynamic profiles, FibroGen seeks to selectively harness and direct HIF-mediated biological pathways in different tissues to address organ-specific tissue damage and pathophysiologies.