pharmacodynamic


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Related to pharmacodynamic: pharmacokinetic

phar·ma·co·dy·nam·ic

(far'mă-kō-dī-nam'ik),
Relating to drug action.

phar·ma·co·dy·nam·ic

(fahr'mă-kō-dī-nam'ik)
Relating to drug action, particularly at the receptor level.
References in periodicals archive ?
According to the company, it is planning two initial studies designed to assess the safety, tolerability, pharmacodynamics and pharmacokinetics of d-Methadone in healthy subjects.
We anticipate that the assay developed using funds from the SBIR grant will be suitable and useful against a wide range of cancer cells, providing researchers with a robust tool to monitor Akt activity both in basic cancer research and in the context of pharmacodynamic drug studies.
The results show that EP ''target-specific pharmacodynamic biomarkers can be reliably measured in CTCs isolated from patients, '' OncLive said citing study authors.
pneumoniae, several pharmacodynamic studies have demonstrated that a target AU[C.
We expect that safety and pharmacodynamic mechanism of action data from our IMO-3100 clinical trials in healthy subjects will help us move rapidly into clinical evaluation of IMO-3100 in selected autoimmune disease indications.
Study Results Demonstrate Tolerability, Pharmacokinetics, and Pharmacodynamic Effects, with Trial Continuing in Dose Escalation -
Secondary objectives are to characterise the pharmacokinetic profile of IMO-3100 and to assess the pharmacodynamic mechanism of action through measurement of the ex vivo response of PBMCs to TLR7 and TLR9 agonists.
Profitable Opportunities in Pharmacodynamic Assay Development.
The pharmacodynamic effects observed across diverse tumor types suggest that XL765 may have utility in a variety of cancers.
Both the MLN4924 and MLN8237 programs are using pharmacodynamic tools, which assist us in translating our pre-clinical findings into cancer patients.
EP42675 was well tolerated in 100 healthy subjects enrolled in five phase I, including single-dose and multiple ascending dose studies and a pharmacodynamic interaction study with a combination of oral aspirin and clopidogrel.