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medicinal chemistry in its application to the analysis, development, preparation, and the manufacture of drugs.
Farlex Partner Medical Dictionary © Farlex 2012
medicinal chemistryThe discipline involved in discovering and developing new chemical compounds into useful medicines; the analysis, development, preparation, and manufacture of drugs.
Medicinal chemistry begins after biologically validated targets have been screened against a diverse library of compounds and promising initial chemical structures (known as hits) have been identified; the hits are then optimised to improve their therapeutic index—potency vs. toxicity.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
pharmacochemistry(făr″mă-kō-kĕm′ĭs-trē) [″ + chemeia, chemistry]
Medical Dictionary, © 2009 Farlex and Partners