pharmacochemistry


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phar·ma·ceu·ti·cal chem·is·try

medicinal chemistry in its application to the analysis, development, preparation, and the manufacture of drugs.

medicinal chemistry

The discipline involved in discovering and developing new chemical compounds into useful medicines; the analysis, development, preparation, and manufacture of drugs.

Medicinal chemistry begins after biologically validated targets have been screened against a diverse library of compounds and promising initial chemical structures (known as hits) have been identified; the hits are then optimised to improve their therapeutic index—potency vs. toxicity.

pharmacochemistry

(făr″mă-kō-kĕm′ĭs-trē) [″ + chemeia, chemistry]
Pharmaceutical chemistry.
References in periodicals archive ?
A voucher specimen is kept in the Department of Pharmacobotany, Institute of Pharmacochemistry, Tbilisi, Georgia (Tubers no: 73700).
colchica is kept in the Department of Pharmacobotany, Institute of Pharmacochemistry, Tbilisi, Georgia (leaves no: 70996).