phagosome


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Related to phagosome: Macrophages, autophagosome

phagosome

 [fag´o-sōm]
a membrane-bound vesicle in a phagocyte containing the phagocytized material.

phag·o·some

(fag'ō-sōm),
A vesicle that forms around a particle (bacterial or other) within the phagocyte that engulfed it, separates from the cell membrane, and then fuses with and receives the contents of cytoplasmic granules (lysosomes), thus forming a phagolysosome in which digestion of the engulfed particle occurs.
[phago- + G. sōma, body]

phagosome

/phago·some/ (fag´o-sōm) a membrane-bound vesicle in a phagocyte containing the phagocytized material.

phagosome

(făg′ə-sōm′)
n.
A membrane-bound vesicle found in a cell by an inward folding of the cell membrane to hold foreign matter taken into the cell by phagocytosis.

phagosome

[fag′əsōm]
a membrane-bound cytoplasmic vesicle within the phagocyte that engulfs it. The vesicle contains phagocytized materials and may fuse with a lysosome, forming a phagolysosome within which the lysosome digests the phagocytized material. Also called phagocytic vacuole.

phag·o·some

(fag'ō-sōm)
A vesicle that forms around a particle (bacterial or other) within the phagocyte that engulfed it, separates from the cell membrane, then fuses with and receives the contents of cytoplasmic granules (lysosomes), thus forming a phagolysosome in which digestion of the engulfed particle occurs.
[phago- + G. sōma, body]

phagosome

The vacuole, formed within a PHAGOCYTE, that surrounds material that has been taken up by cell membrane invagination. A phagosome may fuse with a lysosome to provide digestive enzyme.

phagosome

a membrane-bound vesicle in a phagocyte containing the phagocytized material. Called also a phagocytic vacuole.
References in periodicals archive ?
Regulation of legionella phagosome maturation and infection through flagellin and host Ipaf.
Deretic, "Mechanism of inducible nitric oxide synthase exclusion from mycobacterial phagosomes," PLoS Pathogens, vol.
NRAMP1 gene is expressed in monocyte/macrophages and has key roles in phagosome maturation and cell activation.
Promastigotes attach to mononuclear phagocytes and are taken up by phagocytosis into a phagosome, which fuse with lysosomes to form the phagolysosome.
Once the EB attaches to the columnar epithelial cell it is incorporated into the cell by a process of pinocytosis, in which the organism is surrounded with a phagosome membrane (Friss 1972).
Immunologists, microbial geneticists, cell and molecular biologists, and other scientists from around the world outline the biology underlying different phagocyte lineages, the properties and functions of the phagosome, the link between innate and acquired immunity, the development of specific cellular and humoral immune responses, and different infection models and how the phagocytes respond to control the infection and improve protective immunity.
monocytogenes activates transcription of seeligerolysin and leads to bacterial escape from the phagosome of infected mammalian cells.
Generally, the Ehrlichia species tend to infect leukocytes, where they enter the cell by endocytosis and once inside the host cell, they inhibit the fusion of the phagosome and lysosome.
Phagosome isolation by detergent free method was used to study role of Lyn in phagocytosis.
Blander JM, Medzhitov R (2004) Regulation of phagosome maturation by signals from toll-like receptors.
Each phagocytic event results in the formation of a phagosome into which reactive oxygen species and hydrolytic enzymes are secreted.
Modeling the reactions of superoxide and myeloperoxidase in the neutrophil phagosome.