phagocytosis

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phagocytosis

 [fag″o-si-to´sis]
the engulfing of microorganisms or other cells and foreign particles by phagocytes. adj., adj phagocytot´ic.
Phagocytosis. From Damjanov, 2000.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

phag·o·cy·to·sis

(fag'ō-sī-tō'sis),
The process of ingestion and digestion by cells of solid substances, for example, other cells, bacteria, bits of necrotic tissue, foreign particles.
See also: endocytosis.
[phagocyte + G. -osis, condition]
Farlex Partner Medical Dictionary © Farlex 2012

phagocytosis

(făg′ə-sī-tō′sĭs)
n.
The engulfing and ingestion of foreign bodies such as bacteria or other cells by phagocytes or certain protists, such as amoebas.

phag′o·cy·tot′ic (-tŏt′ĭk) adj.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

phag·o·cy·to·sis

(fāg'ō-sī-tō'sis)
The process of ingestion and digestion by cells of solid substances, e.g., other cells, bacteria, bits of necrotic tissue, foreign particles.
See also: endocytosis
[phagocyte + G. -osis, condition]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

phagocytosis

(fag?o-si-to'sis) [? + ? + osis, condition]
Enlarge picture
PHAGOCYTOSIS
A three-stage process by which phagocytes (neutrophils, monocytes, and macrophages) engulf and destroy microorganisms, other foreign antigens, and cell debris. Generally, these substances must be covered with opsonins, such as antibodies or complement, to initiate binding with cell receptors on the phagocytes, the first stage in phagocytosis. In the second stage, the particle is engulfed and enclosed in a vacuole (phagosome). During the third stage, the phagosome merges with lysosomes whose enzymes destroy the engulfed particle. See: illustration; defensin; lysozyme; macrophage; neutrophil; oxygen radical

Most bacteria are killed during phagocytosis by oxygen radicals, which are formed during the respiratory burst when phagosomes and lysosomes merge. When oxygen radical production is excessive, tissue damage occurs. Lysozymes, defensins, and bacteriocidal permeability-increasing (BPI) protein also destroy bacteria and other organisms; their actions do not depend on the generation of oxygen radicals.

induced phagocytosis

Phagocytosis that is stimulated by the presence of opsonins such as antibodies.

spontaneous phagocytosis

Phagocytosis that occurs in the absence of opsonins.
Medical Dictionary, © 2009 Farlex and Partners

phagocytosis

The envelopment and destruction of bacteria or other foreign bodies by PHAGOCYTES.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005

phagocytosis

the ingestion of materials (subcellular particles, cells) from the outside of a cell into its interior, forming a cytoplasmic vacuole.
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005

Phagocytosis

A process by which a white blood cell envelopes and digests debris and microorganisms to remove them from the blood.
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.

phagocytosis 

The process of ingestion of solid substances (e.g. cells, bacteria, parts of necrosed tissue) by cells and transported to a site within the cell where it is broken down by lysosomal enzymes.
Millodot: Dictionary of Optometry and Visual Science, 7th edition. © 2009 Butterworth-Heinemann

phag·o·cy·to·sis

(fāg'ō-sī-tō'sis)
Process of ingestion and digestion by cells of solid substances.
[phagocyte + G. -osis, condition]
Medical Dictionary for the Dental Professions © Farlex 2012
References in periodicals archive ?
Furthermore, the neuron phagocytotic activity of microglia had significantly diminished in STIM[1.sup.-/-] microglia.
To compare phagocytosis activity in WT and STIM[1.sup.-/-] microglia, resting and LPS-stimulated (100 ng/mL for 24 h) phagocytotic activities were tested with engulfment of E.
Mechanism of phagocytosis in Dictyostelium discoideum: phagocytosis is mediated by different recognition sites as disclosed by mutants with altered phagocytotic properties.
The function of these matured phagocytotic cells will be the recognition, phagocytosis, and killing of the infecting Candida.
This "harvesting" via phagocytotic degradation has also been found in Riftia pachyptila (Bosch and Grasse, 1984), in symbiont-harboring oligochaeta (Giere and Langheld, 1987), and in bivalves (Fiala-Medioni and Felbeck, 1990).
Recent research has shown that FKN attenuated the LPS-induced production of IL-1, IL-6, and TNF-[alpha] by rat and mouse microglia, which are phagocytotic cells that are responsible for cytokine production in the CNS [56].
Microglia can rapidly respond to infectious and traumatic stimuli and adopt a "phagocytotic" nature.
RSA59-infected spinal cords showed significant myelin loss and accumulation of phagocytotic microglia within plaques as observed earlier (Supplementary Figures 2(b) and 2(c)).
Similarly, in vitro treatment of TAM with AGP and ABP resulted in increase of phagocytotic activity.
sibthorpioides extract on the phagocytotic activity of the reticuloendothelial system, the index of blood clearance was measured with Indian ink as the granular foreign body.
sibthorpioides could functionally and structurally damage tumor cells, as well as help improve phagocytotic activity and enhance immune function.
Microglial and/or macrophage phagocytotic activity [3] and T-leukocyte infiltration [5] are upregulated in damaged areas of the midbrain of PD patients and in the brains of MPTP-treated mice, thus giving rise to the death of DA neurons.