phagocytosis


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phagocytosis

 [fag″o-si-to´sis]
the engulfing of microorganisms or other cells and foreign particles by phagocytes. adj., adj phagocytot´ic.
Phagocytosis. From Damjanov, 2000.

phag·o·cy·to·sis

(fag'ō-sī-tō'sis),
The process of ingestion and digestion by cells of solid substances, for example, other cells, bacteria, bits of necrotic tissue, foreign particles.
See also: endocytosis.
[phagocyte + G. -osis, condition]

phagocytosis

(făg′ə-sī-tō′sĭs)
n.
The engulfing and ingestion of foreign bodies such as bacteria or other cells by phagocytes or certain protists, such as amoebas.

phag′o·cy·tot′ic (-tŏt′ĭk) adj.

phag·o·cy·to·sis

(fāg'ō-sī-tō'sis)
The process of ingestion and digestion by cells of solid substances, e.g., other cells, bacteria, bits of necrotic tissue, foreign particles.
See also: endocytosis
[phagocyte + G. -osis, condition]

phagocytosis

(fag?o-si-to'sis) [? + ? + osis, condition]
Enlarge picture
PHAGOCYTOSIS
A three-stage process by which phagocytes (neutrophils, monocytes, and macrophages) engulf and destroy microorganisms, other foreign antigens, and cell debris. Generally, these substances must be covered with opsonins, such as antibodies or complement, to initiate binding with cell receptors on the phagocytes, the first stage in phagocytosis. In the second stage, the particle is engulfed and enclosed in a vacuole (phagosome). During the third stage, the phagosome merges with lysosomes whose enzymes destroy the engulfed particle. See: illustration; defensin; lysozyme; macrophage; neutrophil; oxygen radical

Most bacteria are killed during phagocytosis by oxygen radicals, which are formed during the respiratory burst when phagosomes and lysosomes merge. When oxygen radical production is excessive, tissue damage occurs. Lysozymes, defensins, and bacteriocidal permeability-increasing (BPI) protein also destroy bacteria and other organisms; their actions do not depend on the generation of oxygen radicals.

induced phagocytosis

Phagocytosis that is stimulated by the presence of opsonins such as antibodies.

spontaneous phagocytosis

Phagocytosis that occurs in the absence of opsonins.

phagocytosis

The envelopment and destruction of bacteria or other foreign bodies by PHAGOCYTES.

phagocytosis

the ingestion of materials (subcellular particles, cells) from the outside of a cell into its interior, forming a cytoplasmic vacuole.

Phagocytosis

A process by which a white blood cell envelopes and digests debris and microorganisms to remove them from the blood.

phagocytosis 

The process of ingestion of solid substances (e.g. cells, bacteria, parts of necrosed tissue) by cells and transported to a site within the cell where it is broken down by lysosomal enzymes.

phag·o·cy·to·sis

(fāg'ō-sī-tō'sis)
Process of ingestion and digestion by cells of solid substances.
[phagocyte + G. -osis, condition]
References in periodicals archive ?
Phagocytosis of spermatozoa and of residual bodies discarded by maturing spermatids has been described in detail for NPs in Anthocidaris crassispina (Reunov et al., 2004a, b).
Fluorescence Microscopy for Quantification of Phagocytosis. RAW264.7 cells were plated onto 12 or 24 well plates and pretreated for 8 hrs with fisetin (20 [micro]M), CSE (5%), chloroquine (10 [micro]M), and CFTR(inh)-172 (inhibitor; 10 [micro]M) or transfected for 24 hrs with TFEB-Mission[TM] shRNA.
To clarify whether the CD47-SIRP[alpha] signal contributes to the immune evasion mediated by TAMs, we perform a phagocytosis assay in vitro and establish the xenograft EC model to test the antitumor activity of CD47 blockade therapy.
Here, we provide the first comprehensive analysis of MMP-13 involvement in the biology of DC and the functional changes resulting from the inhibition of MMP-13, including DC maturation, apoptosis, and phagocytosis.
This can be an advantageous mechanism for neoplastic cells over their normal counterparts, which allows the former to evade phagocytosis by cells of the innate immune system.
Dex treatment enhanced phagocytic activity of DCs following aspergillus conidia infection, compared to the control group (phagocytosis rates: 91.0% [+ or -] 3.4% in Dex group; 67.1% [+ or -] 10.1% in the control group, t = 5.493, P = 0.001); whereas IFN-a did not enhance phagocytic activity of DCs following aspergillus conidia infection (phagocytosis rate in IFN-a group: 66.7% [+ or -] 5.9%, t = 0.084, P = 0.935).
"Among the genes we saw altered were many involved in phagocytosis, which is the first time this has been shown," Feinstein said.
Influence of PLGA-PEG Percentage to Phagocytosis Hindrance Capability.
The neutrophil-tumor cell emperipolesis, entosis, and/or phagocytosis (cannibalism) may be a spectrum of the cell-in-cell phenomenon.
When macrophages encounter maresins, they increase phagocytosis and efferocytosis, resulting in the removal of microbes.
Similar to AMs, several density-defined populations have been identified exhibiting differential prostaglandin secretion, migration, and phagocytosis capabilities [51-53].
There was reduction in phagocytosis percentage of macrophages with increase in dose.