phagocytosis

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phagocytosis

 [fag″o-si-to´sis]
the engulfing of microorganisms or other cells and foreign particles by phagocytes. adj., adj phagocytot´ic.
Phagocytosis. From Damjanov, 2000.

phag·o·cy·to·sis

(fag'ō-sī-tō'sis),
The process of ingestion and digestion by cells of solid substances, for example, other cells, bacteria, bits of necrotic tissue, foreign particles.
See also: endocytosis.
[phagocyte + G. -osis, condition]

phagocytosis

/phago·cy·to·sis/ (-si-to´sis) the engulfing of microorganisms or other cells and foreign particles by phagocytes.phagocytot´ic
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Phagocytosis.

phagocytosis

(făg′ə-sī-tō′sĭs)
n.
The engulfing and ingestion of foreign bodies such as bacteria or other cells by phagocytes or certain protists, such as amoebas.

phag′o·cy·tot′ic (-tŏt′ĭk) adj.

phagocytosis

[fag′əsītō′sis]
Etymology: Gk, phagein + kytos + osis, condition
the process by which certain cells engulf and destroy microorganisms and cellular debris. The process includes five steps: (1) invagination, (2) engulfment, (3) internalization and formation of the phagocyte vacuole, (4) fusing of lysosomes to digest the phagocytosed material, and (5) release of digested microbial products. phagocytize, v.
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Phagocytosis

phag·o·cy·to·sis

(fāg'ō-sī-tō'sis)
The process of ingestion and digestion by cells of solid substances, e.g., other cells, bacteria, bits of necrotic tissue, foreign particles.
See also: endocytosis
[phagocyte + G. -osis, condition]

phagocytosis

(fag?o-si-to'sis) [? + ? + osis, condition]
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PHAGOCYTOSIS
A three-stage process by which phagocytes (neutrophils, monocytes, and macrophages) engulf and destroy microorganisms, other foreign antigens, and cell debris. Generally, these substances must be covered with opsonins, such as antibodies or complement, to initiate binding with cell receptors on the phagocytes, the first stage in phagocytosis. In the second stage, the particle is engulfed and enclosed in a vacuole (phagosome). During the third stage, the phagosome merges with lysosomes whose enzymes destroy the engulfed particle. See: illustration; defensin; lysozyme; macrophage; neutrophil; oxygen radical

Most bacteria are killed during phagocytosis by oxygen radicals, which are formed during the respiratory burst when phagosomes and lysosomes merge. When oxygen radical production is excessive, tissue damage occurs. Lysozymes, defensins, and bacteriocidal permeability-increasing (BPI) protein also destroy bacteria and other organisms; their actions do not depend on the generation of oxygen radicals.

induced phagocytosis

Phagocytosis that is stimulated by the presence of opsonins such as antibodies.

spontaneous phagocytosis

Phagocytosis that occurs in the absence of opsonins.

phagocytosis

The envelopment and destruction of bacteria or other foreign bodies by PHAGOCYTES.

phagocytosis

the ingestion of materials (subcellular particles, cells) from the outside of a cell into its interior, forming a cytoplasmic vacuole.

Phagocytosis

A process by which a white blood cell envelopes and digests debris and microorganisms to remove them from the blood.

phagocytosis

process of ingestion and digestion of particles, foreign material, necrotic or degenerate tissue or bacteria by phagocytic cells, e.g. macrophages

phagocytosis 

The process of ingestion of solid substances (e.g. cells, bacteria, parts of necrosed tissue) by cells and transported to a site within the cell where it is broken down by lysosomal enzymes.

phag·o·cy·to·sis

(fāg'ō-sī-tō'sis)
Process of ingestion and digestion by cells of solid substances.
[phagocyte + G. -osis, condition]

phagocytosis (fag´əsītō´sis),

n the engulfing of microorganisms, cells, and other substances by phagocytes. See also phagocyte.

phagocytosis

the engulfing of microorganisms or other cells and foreign particles by phagocytes.
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Phagocytosis. By permission from Roitt I, Brostoff J, Male D, Immunology, Mosby, 2001