phage display library

phage display library

a collection of PHAGE CLONES carrying various DNA fragments for the display of a range of PEPTIDES/PROTEINS. Importantly, there is a physical link between each displayed protein and the DNA encoding it, hence vast numbers of protein variants can be screened and the corresponding DNA sequence of each identified. See also PHAGE DISPLAY.
References in periodicals archive ?
The PD-1 antibody used in this study was developed using Eureka's proprietary E-ALPHA phage display library for the discovery and engineering of human antibodies.
(1996) Human antibodies with subnanomolar affinities isolated from a large nonimmunized phage display library. Nat.
Agenus' CPM discovery capabilities now include a broad and complementary suite of technologies, including a phage display library exclusively licensed from IONTAS, Agenus' mammalian Retrocyte Display, and the SECANT yeast display platforms, as well as a cell line development technology acquired from Selexis.
This phage display library contains individual phage clones which displayed the random heptapeptide on minor coat protein pIII.
Mazooji, and T Quinn, "[alpha]-helically constrained phage display library," Protein Engineering, vol.
Evaluation of a nanobody phage display library constructed from a Brucella-immunised camel.
Shirley, NY, September 08, 2013 --(PR.com)-- The services range from phage display library construction (such as cDNA libraries, peptide libraries and scFv/Fab antibody libraries) to phage display screening (including screening of phage display peptide, cDNA and scFv/Fab libraries).
In the present work, a heptapeptide phage display library was screened against TNF-[alpha], as a first step in the development of new molecular imaging tools for detecting inflammation in chronic inflammatory pathologies and diseases of uncertain diagnosis.
The agreement involves multiple proprietary XOMA antibody research and development technologies, including a new XOMA phage display library, and a suite of integrated information and data management systems.
Nastech published in the March, 2007 issue of the Journal of Biological Chemistry results that demonstrate the use of a proprietary phage display library to screen protein to protein interactions and protein-DNA interactions.
In this study we used a random hepta-peptide phage display library to identify the mimotope of the MAb38G6.
Its core technology platforms center around its proprietary ARTEMIS T cell receptor platform and proprietary E-ALPHA phage display library for the discovery and engineering of human antibodies against intracellular targets via the MHCI complex.