phacolytic glaucoma

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Related to phacolytic glaucoma: phacoemulsification

phac·o·lyt·ic glau·co·ma

glaucoma secondary to hypermature cataract and occlusion of the trabecular drainage meshwork by lens material.

phacolytic glaucoma

an abnormal condition characterized by an acute autoimmune reaction of the eye. It is caused by hypersensitivity of the eye to the protein of the crystalline lens and commonly follows trauma to the crystalline lens or cataract surgery. Associated symptoms include swelling and inflammation of the eye, severe pain, and blurred vision. The substance of the lens is invaded by polymorphonuclear cells and mononuclear phagocytes. Accurate diagnosis must differentiate between this condition and infectious endophthalmitis. Therapy is supportive and commonly includes the administration of corticosteroids and atropine. Refractory cases may require surgical removal of the lens. Also called endophthalmitis phacoanaphylactica. Compare uveitis.


a group of diseases of the eye characterized by increased intraocular pressure, resulting in pathological changes in the optic disk and typical visual field defects, and eventually blindness if not treated successfully. Uncommon in domestic animals, except in dogs where several breeds are predisposed.
The normal eye is filled with aqueous humor in an amount carefully regulated to maintain the shape of the eyeball. In glaucoma, the balance of this fluid is disturbed; fluid is formed more rapidly than it leaves the eye, and pressure builds up. The increased pressure damages the retina. If not relieved by proper treatment, the pressure will eventually damage the optic nerve, causing blindness.

absolute glaucoma
end-stage glaucoma with buphthalmos and severe degenerative changes.
aphakic glaucoma
forward displacement of the posterior lens capsule and vitreous body with incarceration in the pupil; usually occurs after cataract surgery.
closed-angle glaucoma
one in which the iridocorneal angle is obstructed, either due to collapse or interference with drainage by the iris or connective tissue. The cause may be congenital (goniodysgenesis) or acquired, due to an abnormality of the lens, anterior chamber or iris.
congenital glaucoma
that due to defective development of the structures in and around the anterior chamber of the eye, and resulting in impairment of drainage. See also goniodysgenesis.
narrow-angle glaucoma
a form of primary glaucoma caused by abnormal development of the iridocorneal angle. See also goniodysgenesis.
open-angle glaucoma
a form of glaucoma in which there is no detectable abnormality of the iridocorneal angle, but drainage is obstructed by elements in the aqueous humor, luxation of the lens, or elevated episcleral venous pressure. In some cases, particularly in predisposed breeds of dogs such as beagles, no contributing factors are detectable.
phacolytic glaucoma
leakage of lens material from a hypermature cataract causes anterior uveitis that impedes aqueous outflow.
primary glaucoma
increased intraocular pressure occurring in an eye with no other eye disease being present.
secondary glaucoma
increased intraocular pressure due to disease or injury to the eye.
References in periodicals archive ?
6] Slit lamp examination of phacolytic glaucoma typically reveals microcystic corneal edema, and the anterior chamber contains intense flare, large cells (Macrophages), and aggregates of white material and iridescent or hyperrefringent particles.
CONCLUSION: Immediate paracentesis in phacolytic glaucoma patients is an effective procedure which causes significant reduction in intraocular pressure and improvement in postoperative visual acuity which obliterated the requirement for Inj.
Cholesterol crystals in aqueous humor of the eye with phacolytic glaucoma.
Ocular snow storm: an unusual presentation of phacolytic glaucoma.
All the results in our study are comparable to other studies except that number of patients with phacolytic glaucoma was more than phacomorphic glaucoma in our study.
Phacomorphic glaucoma was present in 296 patients (72%) and phacolytic glaucoma in 115 (28%).
57% with phacomorphic and 61% with phacolytic glaucoma recovered visual acuity of 6/12 or better.
Out of these 15(60%) patients had phacomorphic and 10(40%) had phacolytic glaucoma respectively.