pertactin


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per·tac·tin

(per-tak'tin),
The primary receptor of Bordetella pertussis, the antigenicity of which improves the effectiveness of pertussis vaccines.
[pertussis + act + -in]

per·tac·tin

(pĕr-tak'tin)
An antigenic material produced by Bordetella pertussis used to improve the effectiveness of pertussis vaccines.
[pertussis + act + -in]
References in periodicals archive ?
In Australia, the 3-component ACV (containing pertactin [Prn], pertussis toxin [Ptx], and filamentous hemagglutinin [Fha]) has been more widely used than the 5-component ACV (which also contains fimbrial antigen: Fim2 and Fim3).
perfussis filamentous haemagglutinin and at least 8 micrograms pertactin. Estimated number of doses to be delivered: 2017, 500 units; 2018, 500 units.
Additionally, aPs rely heavily on pertactin as a target antigen, (3) likely less than WCP, given that WCP contained all pertussis antigens rather than just the three to five purified antigens in aPs.
Noninferiority criteria were met for the following antigens contained in coadministered vaccines: 13 serotypes of Streptococcus pneumoniae; poliovirus types 1,2, and 3; hepatitis B; pertussis toxin, filamentous hemagglutinin, and pertactin; diphtheria; and tetanus.
Pulsed-field gel electrophoresis, pertactin, pertussis toxin S I subunit polymorphisms, and surfaceome analysis of vaccine and clinical Bordetella pertussis strains.
CDC biologist Lucia Pawloski and her colleagues screened 1,300 pertussis microbe samples collected from patients from 1935 to 2012 and found that 306 seemed unable to make pertactin. All but one of those dated to 2010 or later, suggesting that the pathogen morphed recently.
TABLE 1 Available tetanus-diphtheria-pertussis vaccines (5) FDA-approved Trade name Manufacturer age for use* (y) Boostrix GlaxoSmithKline [greater than or Biologicals equal to] 10 Adacel Sanofi Pasteur 11-64 Pertussis antigens (mcg) Trade name PT FHA PRN FIM Boostrix B B 2.5 -- Adacel 2.5 5 3 5 ([dagger]) Diphtheria Tetanus Trade name toxoid (Lf) toxoid (Lf) Boostrix 2.5 5 Adacel 2 5 FDA, Food and Drug Administration; FHA, filamentous hemagglutinin; HIM, fimbriae; Lf, limit of flocculation units; PRN, pertactin; PT, pertussis toxin.
These factors include toxins such as adenylate cyclase toxin, dermonecrotic toxin, the type III secretion system, and adhesins such as filamentous hemagglutinin, pertactin, and fimbriae [15, 16].
Blood samples were measured for pertussis antigens, including pertussis toxoid, filamentous hemagglutinin, pertactin, and fimbriae, by enzyme-linked immunosorbent assay.
Blood samples were measured for pertussis antigens, including pertussis toxold, filamentous hemagglutinin, pertactin, and fimbriae, by enzyme-linked immunosorbent assay.
A substantial reduction in primary antibody response for all 10 pneumococcal conjugate vaccine serotypes and Hib polysaccharide, diphtheria, tetanus and pertactin antigens was found in the paracetamol group.
Pertactin, an Arg-Gly-Asp-containing Bordetella pertussis surface protein that promotes adherence of mammalian cells.