persistent hyperplastic primary vitreous
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vitreous, persistent hyperplastic primary (PHPV)
A congenital, abnormal vitreous development characterized by a retrolental mass formed by remnants of the hyaloid system and tunica vasculosa lentis. The eye presents with leukocoria and there may also be cataract and congenital glaucoma. Treatment should begin as early in life as possible to avoid the risk of damage to the globe and amblyopia. See hyaloid artery; hyaloid remnant.