* Postoperative, prophylactic, single dose systemic MTX may reduce the incidence of persistent ectopic pregnancy
In the same study, the rate of persistent ectopic pregnancy
after laparotomy with tube conserving surgery was 3-5% and after laparoscopy was 3-20%.
Weekly quantitative [beta]-hCG testing is required to rule out persistent ectopic pregnancy, which occurs in 5 % to 8 % of patients following salpingostomy.
Methotrexate may be used for primary treatment of ectopic pregnancy, for persistent ectopic pregnancy following tubal sparing surgery, as prophylaxis to reduce persistent ectopic pregnancy following salpingostomy, and in cornual and cervical pregnancies.
Persistent ectopic pregnancy: an argument for heightened vigilance and patient compliance.
Tulandi shares valuable insight on interstitial pregnancy as well as persistent ectopic pregnancy
Methotrexate prophylaxis for persistent ectopic pregnancy
after conservative treatment by salpingostomy.
Persistent ectopic pregnancy
occurs more often after salpingostomy performed with laparoscopy than after salpingostomy through laparotomy (about 8% compared with 4%).