peroxisomes


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Related to peroxisomes: Glyoxysomes

peroxisomes

Membrane-bound cell organelles containing oxidative enzymes concerned in the detoxification of various molecules and in the breakdown of fatty acids to acetyl-CoA.
References in periodicals archive ?
The team found that medium-chain fatty alcohols could be produced in yeast by targeted expression of fatty acyl-CoA reductase, or TaFAR, in the peroxisome of Saccharomyces cerevisiae.
In cells that lacked Pex11b, peroxisomes weren't divvied up evenly: in some cases, one daughter cell ended up with all of the peroxisomes and the other didn't get any at all.
Peroxisomes are thought to form by the division of pre-exiting peroxisomes after the import of newly synthesized proteins.
2013) reported that 13 tag single nucleotide polymorphisms in the peroxisome proliferator-activated receptor (PPAR) signaling pathway are associated with porcine meat quality traits.
ABCD1 is a protein located in the peroxisomes, compartments of the cell that detoxify chemicals and lipids, and thus the implication of mitochondria in such a disease was not obvious.
2008), we observed a marked hepatomegaly in mPPAR[alpha] mice exposed to TRI that may be due to cellular hypertrophy resulting from increased numbers of peroxisomes (Nakajima et al.
Mice engineered to direct catalase to its usual place, in peroxisomes, showed only a modest increase in life span.
These data indicate that [beta]-oxidation of C24:0 to C16:0 takes place exclusively in peroxisomes and not in mitochondria.
Although peroxisomes are characteristically found in aerobic cells with mitochondria, there is evidence that peroxisomal enzymes occur in the amitochondriate microsporidian Spraguea lophii.
This allowed scientists to distinguish those proteins that partition with peroxisomes from contaminating proteins and develop a catalogue of candidate proteins that occupy the peroxisome in the yeast Saccharomyces cerevisiae.
PPAR[alpha] (NR1C1) is the founding member of the family and was initially isolated as the receptor inducing the hepatic proliferation of peroxisomes in rodents in response to synthetic chemicals.
A function of peroxisomes is to manage the beta-oxidation of long chain fatty acids.

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