peroxisomes


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Related to peroxisomes: Glyoxysomes

peroxisomes

Membrane-bound cell organelles containing oxidative enzymes concerned in the detoxification of various molecules and in the breakdown of fatty acids to acetyl-CoA.
References in periodicals archive ?
If the peroxisomes are damaged or absent, a toxic accumulation of very-long-chain fatty acids occurs.
Zhang et al., "Peroxisomes are signaling platforms for antiviral innate immunity," Cell, vol.
The team found that medium-chain fatty alcohols could be produced in yeast by targeted expression of fatty acyl-CoA reductase, or TaFAR, in the peroxisome of Saccharomyces cerevisiae.
In cells that lacked Pex11b, peroxisomes weren't divvied up evenly: in some cases, one daughter cell ended up with all of the peroxisomes and the other didn't get any at all.
Peroxisomes are thought to form by the division of pre-exiting peroxisomes after the import of newly synthesized proteins.
"ABCD1 is a protein located in the peroxisomes, compartments of the cell that detoxify chemicals and lipids, and thus the implication of mitochondria in such a disease was not obvious.
2008), we observed a marked hepatomegaly in mPPAR[alpha] mice exposed to TRI that may be due to cellular hypertrophy resulting from increased numbers of peroxisomes (Nakajima et al.
The catalase that a cell makes normally goes directly into organelles known as peroxisomes. Rabinovitch's team designed its genetic manipulation so that in some of the mice, the extra catalase went into its normal location.
In an earlier report (3), we indicated that the posterior vacuole had properties of peroxisomes, which function primarily to process very long chain fatty acids (VLCFA) with the assistance of key enzymes, acyl-CoA oxidase (ACOX) and catalase.

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