Peroxisome proliferator-activated receptor-gamma modulates differentiation of human trophoblast in a ligand-specific manner.
Drew, "
Peroxisome proliferator-activated receptor-gamma agonists inhibit the activation of microglia and astrocytes: implications for multiple sclerosis," Journal of Neuroimmunology, vol.
The researchers identified that butyrate activates
peroxisome proliferator-activated receptor-gamma (PPAR-gamma) in colonocytes which inactivated nitric oxide synthase 2 thereby reducing the nitrate production.
Protective effect of
peroxisome proliferator-activated receptor-gamma agonists on activated renal proximal tubular epithelial cells in IgA nephropathy.
Thiemermann, "The
peroxisome proliferator-activated receptor-gamma ligand 15-deoxy-delta12,14 prostaglandin J2 reduces the organ injury in hemorrhagic shock," Shock, vol.
Peroxisome proliferator-activated receptor-gamma activates p53 gene promoter binding to the nuclear factor-kappaB sequence in human MCF7 breast cancer cells.
Researchers also found that long-term feeding of a HF diet to mice caused obesity and glucose intolerance with increased fat volume, fat size and
peroxisome proliferator-activated receptor-gamma (PPAR[gamma]) protein.
Twenty-four hours after the last training bout a subgroup of mice (n = 9-11/group) were euthanized, and brain (brain stem, cerebellum, cortex, frontal lobe, hippocampus, hypothalamus, and midbrain) and muscle (soleus) tissues were isolated for analysis of mRNA expression of
peroxisome proliferator-activated receptor-gamma coactivator-1-alpha (PGC-1 [alpha]), Silent Information Regulator T1 (SIRT1), citrate synthase (CS), and mitochondrial DNA (mtDNA) using RT-PCR.
This maturation is a complex process known as adipogenesis, in which
Peroxisome Proliferator-Activated Receptor-Gamma (PPAR-[gamma]) and
Peroxisome proliferator-activated receptor-Gamma Coactivator 1 alpha (PGC-1[alpha]) are both indispensable.
Now they have revealed the mechanism by which the natural drug abscisic acid interacts with this protein, known as
peroxisome proliferator-activated receptor-gamma, to block inflammation and the subsequent onset of disease.
Genetic polymorphism of
peroxisome proliferator-activated receptor-gamma 2 Pro12Ala on ethnic susceptibility to diabetes in Uygur, Kazak and Han subjects.
& Arslan, M., Pro12Ala polymorphism of the
peroxisome proliferator-activated receptor-gamma gene in first-degree relatives of subjects with polycystic ovary syndrome.