peroxisome


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peroxisome

 [pĕ-roks´ĭ-sōm]
a microbody found in vertebrate animal cells, especially kidney and liver cells, that contains urate oxidase, amino acid oxidase, catalase, and other enzymes.

pe·rox·i·some

(pĕ-rok'si-sōm),
A membrane-bound organelle occurring in many eukaryotic cells that often has an electron-dense crystalline inclusion containing catalase, urate oxidase, and other oxidative enzymes relating to the formation and degradation of H2O2; thought to be important in detoxifying various molecules and in catalyzing the breakdown of fatty acids to acetyl-CoA; an absence of peroxisomes is found in patients with Zellweger syndrome.
[peroxide + G. sōma, body]

peroxisome

(pə-rŏk′sĭ-sōm′)
n.
A cell organelle containing a large number of enzymes, including catalase and oxidase, that break down long-chain fatty acids and other organic molecules. The hydrogen peroxide produced by these reactions is also broken down within the peroxisome.

per·ox′i·som′al (-sō′məl) adj.

pe·rox·i·some

(pĕr-ok'si-sōm)
A membrane-bound organelle occurring in nearly all eukaryotic cells that often contains oxidative enzymes relating to the formation and degradation of H2O2.
Synonym(s): microbody.
[peroxide + G. sōma, body]

peroxisome

an organelle of EUKARYOTE cells which is surrounded by a single unit membrane. Peroxisomes contain PEROXIDASES and may be concerned with the production of molecular oxygen from the breakdown of hydrogen peroxide. They are located near MITOCHONDRIA and plant CHLOROPLASTS, and appear to be involved in CELLULAR RESPIRATION.
References in periodicals archive ?
Tumor necrosis factor-alpha-induced apoptosis of human coronary artery endothelial cells: modulation by the Peroxisome Proliferator-activated receptor-gamma ligand pioglitazone.
Pro12Ala polymorphism in the peroxisome prolif-erator-activated receptor-gamma (PPARgamma) gene in inflammatory bowel disease.
Endothelial cell apoptosis induced by the peroxisome proliferator-activated receptor (PPAR) ligand 15-deoxy-D2, 14-prostaglandin J2.
The rare hereditary disease arises from the dysfunction of so-called peroxisomes. These are tiny bubbles surrounded by a membrane that are mainly responsible for detoxifying the cells.
Once activated, the PPAR/retinoid X receptor heterodimer stimulates peroxisome proliferator response elements (PPRE) in the promoter region of target genes.
SLC15A3 Is Located in Lysosomes, Late Endosomes, and Peroxisomes. SLC15A3 was reported to locate in lysosomal membranes [16, 20].
Most eukaryotic cells, or cells containing a nucleus and organelles, are made up of various microorganisms, including peroxisomes, that are located outside the nucleus in the cytoplasm.
In cells whose peroxisome distribution was disrupted, cell division took longer.
Peroxisome proliferator-activated receptors form a subfamily of the nuclear hormone receptor superfamily.
(1997) Isolation of the human PEX12 gene, mutated in group 3 of the peroxisome biogenesis disorders.
Islinger, "Peroxisome interactions and cross-talk with other subcellular compartments in animal cells," Sub-Cellular Biochemistry, vol.

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