peroxisome


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peroxisome

 [pĕ-roks´ĭ-sōm]
a microbody found in vertebrate animal cells, especially kidney and liver cells, that contains urate oxidase, amino acid oxidase, catalase, and other enzymes.

pe·rox·i·some

(pĕ-rok'si-sōm),
A membrane-bound organelle occurring in many eukaryotic cells that often has an electron-dense crystalline inclusion containing catalase, urate oxidase, and other oxidative enzymes relating to the formation and degradation of H2O2; thought to be important in detoxifying various molecules and in catalyzing the breakdown of fatty acids to acetyl-CoA; an absence of peroxisomes is found in patients with Zellweger syndrome.
[peroxide + G. sōma, body]

peroxisome

/per·ox·i·some/ (-ok´sĭ-sōm)
1. any of the microbodies present in vertebrate animal cells, especially liver and kidney cells, which are rich in the enzymes peroxidase, catalase, d-amino acid oxidase, and, to a lesser extent, urate oxidase.
2. microbody (1).

peroxisome

(pə-rŏk′sĭ-sōm′)
n.
A cell organelle containing a large number of enzymes, including catalase and oxidase, that break down long-chain fatty acids and other organic molecules. The hydrogen peroxide produced by these reactions is also broken down within the peroxisome.

per·ox′i·som′al (-sō′məl) adj.

peroxisome

[pər·ok′si·sōm]
any of the microbodies present in vertebrate animal cells, especially liver and kidney cells, that are rich in the enzymes peroxidase, catalase, d-amino acid oxidase, and, to a lesser extent, urate oxidase. Their functions are not fully understood, but they participate in metabolic oxidations involving hydrogen peroxide, purine metabolism, cellular lipid metabolism, and gluconeogenesis. See microbody.

pe·rox·i·some

(pĕr-ok'si-sōm)
A membrane-bound organelle occurring in nearly all eukaryotic cells that often contains oxidative enzymes relating to the formation and degradation of H2O2.
Synonym(s): microbody.
[peroxide + G. sōma, body]

peroxisome

an organelle of EUKARYOTE cells which is surrounded by a single unit membrane. Peroxisomes contain PEROXIDASES and may be concerned with the production of molecular oxygen from the breakdown of hydrogen peroxide. They are located near MITOCHONDRIA and plant CHLOROPLASTS, and appear to be involved in CELLULAR RESPIRATION.

peroxisome

a membrane-bound body found in vertebrate animal cells, especially kidney and liver cells, that contains urate oxidase, amino acid oxidase, catalase and other enzymes.
References in periodicals archive ?
Xenopus peroxisome proliferator activated receptors: genomic organization, response element recognition, heterodimer formation with retinoid X receptor and activation by fatty acids.
Peroxisome proliferator-activated receptor (PPAR) [alpha], one of the PPAR receptors, is predominantly expressed in the liver (Braissant et al.
Molecular scanning of the human peroxisome proliferator-activated receptor g (hPPARg) gene in diabetic Caucasians: identification of a Pro12Ala PPARg 2 missense mutation.
Molecular cloning, expression and characterization of human peroxisome proliferator activated receptors g1 and g2.
Pleiotropic actions of peroxisome proliferator activated receptors (PPARs) in dysregulated metabolic homeostasis, inflammation and cancer: current evidence and future perspectives.
Researchers from University of California - Davis Health System identified the host receptor peroxisome proliferator receptor gamma (PPARg) as the regulator responsible for maintaining this cycle of protection.
Zellweger Syndrome (ZS) is a rare disease that takes a part in peroxisome biogenesis disorders.
As an oral once-daily administered molecule and a first-in-class compound, it works using dual peroxisome proliferator-activated alpha/delta pathways.
Using a compartmentalized organelle like the peroxisome as a staging ground was what set this study apart from previous work.
Keywords: Diabetes mellitus, Peroxisome proliferator activated receptor gamma (PPAR gamma), Pioglitazone, Telmisartan, Renin angiotensin system (RAS).
The protein Pex11b is associated with the membrane that surrounds the peroxisome, an organelle that helps to free energy from food.
Editor's Note: As possible protective mechanisms for DHEA, the authors note that the hormone is a peroxisome proliferator-activated receptor (PPAR) alpha agonist, as are fibrate drugs currently used to treat high triglyceride levels.

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