alcoholics, Pernicious anaemia
elderly) Ileal pathology Malabsorption Crohn's disease/ulcerative colitis Inflammatory bowel Infection, e.g.
has been reported in a case of IgG and IgM paraproteinemia of the kappa type as well as IgA multiple myeloma.
These problems associated with the diagnosis of Pernicious Anaemia
in particular, and Vitamin B12 Deficiency in general, are illustrated in a recently published survey of over 1,000 members of the Pernicious Anaemia
Society which found that:
 It is important to emphasise that vitamin [B.sub.12] supplementation during pregnancy should be provided for strict vegans and mothers with pernicious anaemia
to avoid irreversible neurological damage in exclusively breastfed babies.
Scientist shows that pernicious anaemia
is an autoimmune disease (the body attacks itself) and occurs when the secretion of gastric mucosal is deficient.
A physically fragile man, who suffered from pernicious anaemia
, he developed a stubborn resistance to persecution and bullying when, as a trainee priest, he was forced to undergo compulsory military training.
My grandfather returned home in from The First World War 1919 apparently unscathed, to marry and start a family - only to discover within a couple of years that the malaria he had caught while fighting in Salonica had left him with pernicious anaemia
(then a terminal disease).
Comparison of hydroxocobalamin and cyanocobalamin in the treatment of pernicious anaemia
. Lancet 1965; 7426:1305-8.
The most common is pernicious anaemia
, in which intrinsic factor secretion has ceased.
See your GP if the corners of your mouth are red and sore and don't heal as this may be a symptom of vitamin B12 deficiency which causes pernicious anaemia
Mr Martyn Hooper, Chair of the UK Pernicious Anaemia
Society gave a most thought-provoking presentation on the Consequences of Vitamin B12 deficiency.
In addition to chronic disease, etiology has also been linked to Vitamin B12 deficiency, celiac disease, nutritional anaemia often due to inadequate dietary iron intake, functional erythropoietin deficiency in diabetic nephropathy, chronic blood loss, intravascular haemolysis due to associated ketoacidosis or associated parasitic or other infections and Autoimmune Polyglandular Syndrome with its associated coeliac disease and pernicious anaemia
.6 Most studies which have looked at morphological classification of anaemia in Type 1 diabetes have found a microcytic hypochromic picture secondary to iron deficiency.