A key aspect of the biologist's question is whether or not JCV normally integrates into permissive cells
, so you must understand this concept as well.
Thus, it is possible that the subsequent replacement of the mature B cell population results in expansion of pre-B cell-harboring latent JC virus that can use these lymphocytes to reach the CNS and to infect permissive cells
, such as oligodendrocytes.
In contrast to our data, previous studies have indicated that the HHV-8-encoded chemokines viral MIP-1 and viral MIP-II may decrease HIV-1 replication by blocking coreceptors necessary for HIV binding and entry into permissive cells
.[18,31,32] The differences in the results are likely due to experimental design.
After following virus growth in all permissive cells
for another 20 h, we harvested supernatants and, to confirm the production of infectious virus particles, we titrated the supernatants by using a plaque assay in Vero cells.
([paragraph]) Feces, respiratory secretions, environmental sewage, and untreated water samples of unknown origin or collected for any purpose at a time and in a geographic area where it was suspected that WPVs or VDVPs were present, and products of such materials in poliovirus permissive cells
or animals (3).
Beginning 1 year after detection of the last case of polio associated with wild poliovirus, laboratories undertaking activities involving wild poliovirus materials or potential wild poliovirus materials in permissive cells
or animals will be notified to initiate high-containment (Biosafety Level [BSL-3] polio) measures.