perivascular inflammation

perivascular inflammation

A nonspecific finding consisting of the “cuffing” of lymphocytres around blood vessels, which occurs in various conditions—e.g., dermatomyositis, polyarteritis and other vasculitides.
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On histopathologic investigation, 56% (5/9) of animals that reached endpoint criteria had mild mononuclear anterior uveitis, with perivascular inflammation composed of lymphocytes primarily in the pars plana of the ciliary body, located near the iridoscleral junction, and scattered within the margins of the trabecular meshwork of the filtration angle (representative animal Jos-1; Table; Figure 3, panels D, H).
Many other histopathological changes were also noticed in the animals of group C such as glomerular sclerosis, mesangial widening, vascular congestion, perivascular inflammation, swelling of the nuclei of the tubular epithelaial cells, fibrinoid change in the afferent arterioles, lobulation of glomeruli and atrophy of glomeruli, however these changes were not observed in a significant number of animals that could be elaborated (Fig.
Considering that perivascular inflammatory response is the most important pathophysiology aspect of Rocky Mountain spotted fever vasculitis, similar CNS MRI findings have been described in other infectious diseases also known to cause perivascular inflammation, such as cryptococcosis and Lyme disease encephalitis.
In addition, in a study, sural nerve biopsies showed prominent axonal degeneration and perivascular inflammation. [2] Therefore, inflammation and altered immunity may also play a role in the pathogenesis of peroneal neuropathy after BS.
It has been speculated that bladder leiomyomas might arise from chromosomal alterations, hormonal disturbances, repeated bladder wall and detrusor infection, perivascular inflammation or dysontogenesis.
The presence of atypical lymphocytes in lymphoma, IgG4-positive plasma cells in IgG4-related Mikulicz's disease, periductal and perivascular inflammation of lymphocytes and intralobular fibrosis in Sjogren's syndrome are the main factors that aid in the differential diagnosis of sarcoidosis.
However, in the following years, isolated IC cases with perivascular inflammation depicted by cross-sectional imaging were reported.
CAA with inflammatory angiitis details perivascular inflammation with multinucleated giant cells associated with amyloid deposition.
Dermatomyositis is a connective tissue disorder caused by perivascular inflammation in the skeletal muscles.
Skin biopsy of the palm revealed epidermolytic hyperkeratosis, a few scattered apoptotic keratinocytes, mild pigment incontinence in the basal layer and perivascular inflammation in the upper dermis.

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