On histopathologic investigation, 56% (5/9) of animals that reached endpoint criteria had mild mononuclear anterior uveitis, with perivascular inflammation
composed of lymphocytes primarily in the pars plana of the ciliary body, located near the iridoscleral junction, and scattered within the margins of the trabecular meshwork of the filtration angle (representative animal Jos-1; Table; Figure 3, panels D, H).
Many other histopathological changes were also noticed in the animals of group C such as glomerular sclerosis, mesangial widening, vascular congestion, perivascular inflammation
, swelling of the nuclei of the tubular epithelaial cells, fibrinoid change in the afferent arterioles, lobulation of glomeruli and atrophy of glomeruli, however these changes were not observed in a significant number of animals that could be elaborated (Fig.
Considering that perivascular inflammatory response is the most important pathophysiology aspect of Rocky Mountain spotted fever vasculitis, similar CNS MRI findings have been described in other infectious diseases also known to cause perivascular inflammation
, such as cryptococcosis and Lyme disease encephalitis.
In addition, in a study, sural nerve biopsies showed prominent axonal degeneration and perivascular inflammation
.  Therefore, inflammation and altered immunity may also play a role in the pathogenesis of peroneal neuropathy after BS.
It has been speculated that bladder leiomyomas might arise from chromosomal alterations, hormonal disturbances, repeated bladder wall and detrusor infection, perivascular inflammation
The presence of atypical lymphocytes in lymphoma, IgG4-positive plasma cells in IgG4-related Mikulicz's disease, periductal and perivascular inflammation
of lymphocytes and intralobular fibrosis in Sjogren's syndrome are the main factors that aid in the differential diagnosis of sarcoidosis.
in pulmonary infections: implications for the diagnosis of lung rejection.
However, in the following years, isolated IC cases with perivascular inflammation
depicted by cross-sectional imaging were reported.
Mediators of perivascular inflammation
in the left ventricle of renovascular hypertensive rats.
CAA with inflammatory angiitis details perivascular inflammation
with multinucleated giant cells associated with amyloid deposition.
Dermatomyositis is a connective tissue disorder caused by perivascular inflammation
in the skeletal muscles.
Skin biopsy of the palm revealed epidermolytic hyperkeratosis, a few scattered apoptotic keratinocytes, mild pigment incontinence in the basal layer and perivascular inflammation
in the upper dermis.