Clinical signs of glaucoma are the loss of neuroretinal tissue (ganglion cells (GCC) and their axons (RNFL)) observed at the peripapillary
rim area of the optic nerve head (ONH), along with visual field loss.
He was looking for volumetric changes in several of the retinal layers: the peripapillary
retinal nerve fiber layer, macular RNFL, ganglion cell layer, inner plexiform layer, outer nuclear layer, outer plexiform layer, and inner nuclear layer.
Foveal (foveal center retinal, parafoveal retinal, and perifoveal), macular inner retinal (superior and inferior), and peripapillary
RNFL thicknesses (superior, inferior, temporal, and nasal) were measured using Fourier-domain optical coherence tomography before surgery and 1 day, 3 days, and 1 week after surgery.
Glaucomatous optic neuropathy is characterized by thinning of the peripapillary
retinal nerve fiber layer (RNFL) and optic disc cupping as a result of axonal and secondary retinal ganglion cell loss.
Time-domain optical coherence tomography (TD-OCT) has previously shown usefulness of peripapillary
RNFL thickness measurement in glaucoma diagnosis, so RNFL has become a proven and widely used parameter for evaluation of glaucoma in routine clinical practice (5-7).
Two fundal distributions of type 6 lesions were evident: isolated or multifocal lesions in the peripheral retina or peripapillary
lesions observed emanating from the optic disc (Figure 2).
Objective: To determine the relationship between mean axial length and mean peripapillary
retinal nerve fibre layer (RNFL) thickness using spectral domain optical coherence tomography (SD OCT) in healthy subjects.
Examination of the Optic Nerve Head (ONH) and peripapillary
RNFL is essential in detecting and monitoring the disease.
Using optical coherence tomography (OCT), the peripapillary
RNFL thickness in major depressive disorder patients and control subjects was measured and compared at each location.
Post normality testing, Pearson correlation coefficient was calculated to evaluate relationship between CCT and VF parameters (MD, PSD), CDR and peripapillary
9 in the left eye with pallor and peripapillary
A recent meta-analysis has documented significant thinning of peripapillary
RNFL in diabetics (both type 1 and type 2), measured by both OCT and scanning laser polarimeter--based studies.